Results 101 to 110 of about 22,464,620 (250)

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Center For Integrated Area Studies, Kyoto University : Integrated Area Studies • Area Studies Support Facilities • Area Studies Informatics, 2015 [PDF]

open access: yes, 2015
1. Welcome to CIAS [1]2. New Approach to Area Studies [2]3. Gateway of Area Studies in Japan [3]4. CIAS Area Informatics Project [4]5. CIAS Prestigious Resources [5]6. International Research Cooperation [7]7.

core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Pedoman Pengelolaan Pengabdian Kepada Masyarakat Universitas Medan Area [PDF]

open access: yes, 2018
14 HalamanAssalaamu’alaikum warohmatulloohi wabarokaatuh, Puji syukur ke hadirat Allah SWT yang telah melimpahkan segala nikmat sehingga buku Pedoman Pengelolaan Pengabdian kepada Masyarakat Universitas Medan Area ini dapat diselesaikan. Buku ini berisi
Universitas Medan Area, Lembaga Penelitian dan Pengabdian Kepada Masyarakat
core   +1 more source

Competing Claims and Contested Boundaries: Legitimating Land Rights in Isiolo District, Northern Kenya Konkurrierende Ansprüche und umstrittene Grenzlinien: Die Legitimierung von Landrechten im Isiolo-Distrikt in Nordkenia

open access: yesAfrica Spectrum, 2011
People from five different ethnic groups share the territory that is Isiolo District, situated in northern Kenya. This article gives an account of the different groups’ claims to land in this inter-ethnic setting, which is located in the border area of ...
Saafo Roba Boye, Randi Kaarhus
doaj  

Supporting Research in Area Studies: a guide for academic libraries [PDF]

open access: yes, 2015
The study of other countries or regions of the world often crosses traditional disciplinary boundaries in the humanities and social sciences. Supporting Research in Area Studies is a comprehensive guide for academic libraries supporting these communities
Pitman, L
core  

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

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