Results 71 to 80 of about 11,092,458 (299)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Sinology: Chinese Intellectual History and Transcultural Studies

open access: yesThe Journal of Transcultural Studies, 2017
In this article I attempt to identify some methodological connections between Chinese intellectual history and transcultural studies in Euro-American academia.
Pablo Blitstein
doaj   +1 more source

Systemism and New Area Studies: An Application to the Integrated Capabilities Framework

open access: yesNew Area Studies, 2020
With the advent of New Area Studies, interdisciplinary research is entering into an exciting era. Application of insights from the humanities to the study of politics already can boast of considerable results.
Patrick James
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Senator William Maclay of Pennsylvania and the early development of the radical tradition [PDF]

open access: yes, 2010
A thesis submitted in part-fulfilment of the requirements of the degree of MA in Area Studies (United States) at the Institute for the Study of the Americas ...
Lafferty, Ben
core  

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

RECONCILING THE GENERAL AND THE UNIQUE AREA STUDIES, CASE STUDIES, AND HISTORY VERSUS THEORETICAL SOCIAL SCIENCE

open access: yesСравнительная политика, 2015
The article examines the problem of relations between the General and the Unique in the social and political sciences. The author highlights the different views on this perspective: some scientists explain specifi c cases by bringing them under general ...
F. Eidlin
doaj   +1 more source

Pitfalls in comparison of coronary artery measurements of Indian population with different geographical area studies. [PDF]

open access: yesIndian Heart J, 2021
Divia Aricatt P   +7 more
europepmc   +1 more source

Circular-Polarization Dependent Cyclotron Resonance in Large-Area Graphene in Ultrahigh Magnetic Fields [PDF]

open access: yes, 2012
Using ultrahigh magnetic fields up to 170 T and polarized midinfrared radiation with tunable wavelengths from 9.22 to 10.67 um, we studied cyclotron resonance in large-area graphene grown by chemical vapor deposition.
A. Rustagi   +17 more
core   +2 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

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