Results 21 to 30 of about 478,663 (300)

1570. Association Between Vancomycin Area Under the Curve (AUC) and Nephrotoxicity [PDF]

open access: yesOpen Forum Infectious Diseases, 2019
Abstract Background It is unclear whether increased vancomycin area under the curve (AUC) contributes to acute kidney injury (AKI) risk. Methods This retrospective cohort study was undertaken to determine whether vancomycin AUC > ...
Poston-Blahnik, Anna, Moenster, Ryan P
openaire   +1 more source

Naringenin alters the pharmacokinetics of ranolazine in part through the inhibition of cytochrome P450 (3A4) and P-glycoprotein

open access: yesFuture Journal of Pharmaceutical Sciences, 2023
Background This study set out to look at how naringenin affected the pharmacokinetics of ranolazine in rats. The pharmacokinetic investigation of ranolazine in rats following oral administration of ranolazine with or without coadministration of ...
Faisal Alotaibi
doaj   +1 more source

The estimated optimism-corrected area under the receiver operating characteristic curve (OC-AUC-ROC), for predictive models developed by different machine learning algorithms and feature selection methods. [PDF]

open access: yes, 2022
The estimated optimism-corrected area under the receiver operating characteristic curve (OC-AUC-ROC), for predictive models developed by different machine learning algorithms and feature selection methods.
Reza Yaesoubi (207900)   +9 more
core   +1 more source

LRMCMDA: Predicting miRNA-Disease Association by Integrating Low-Rank Matrix Completion With miRNA and Disease Similarity Information

open access: yesIEEE Access, 2020
Identifying disease-related microRNAs (miRNAs) is crucial to understanding the etiology and pathogenesis of many diseases. However, existing computational methods are facing a few dilemmas such as lacking “negative samples” (i.e.
Junlin Xu   +8 more
doaj   +1 more source

Evaluation of limited-sampling strategies to calculate AUC(0–24) and the role of CYP3A5 in Chilean pediatric kidney recipients using extended-release tacrolimus

open access: yesFrontiers in Pharmacology, 2023
Background: Kidney transplantation (KTx) requires immunosuppressive drugs such as Tacrolimus (TAC) which is mainly metabolized by CYP3A5. TAC is routinely monitored by trough levels (C0) although it has not shown to be a reliable marker.
Carla Galvez   +11 more
doaj   +1 more source

Do unbalanced data have a negative effect on LDA? [PDF]

open access: yes, 2008
For two-class discrimination, Xie and Qiu [The effect of imbalanced data sets on LDA: a theoretical and empirical analysis, Pattern Recognition 40 (2) (2007) 557–562] claimed that, when covariance matrices of the two classes were unequal, a (class ...
Titterington, D.M., Xue, J.H.
core   +1 more source

Area under the curve (AUC) analysis for the two experiments. [PDF]

open access: yes, 2020
Area under the curve (AUC) analysis for the two experiments.
Huachen Gao (8562048)   +1 more
core   +1 more source

Area under Curve (AUC) comparison. [PDF]

open access: yes, 2013
Area under Curve (AUC) comparison measuring the ability of recovering the original PPI networks: (a) Y_Tong, (b) H_Bind, (c) H_InAct, (d) F_BioGrid, (e) H_BioGrid using embedding space dimensions of 1 to 20.
Lin Zhu (192179)   +3 more
core   +1 more source

A modified Wald interval for the area under the ROC curve (AUC) in diagnostic case-control studies [PDF]

open access: yesBMC Medical Research Methodology, 2014
The area under the receiver operating characteristic (ROC) curve, referred to as the AUC, is an appropriate measure for describing the overall accuracy of a diagnostic test or a biomarker in early phase trials without having to choose a threshold. There are many approaches for estimating the confidence interval for the AUC.
Kottas, Martina   +2 more
openaire   +3 more sources

Prediction performance (area under curve, AUC) of integrative models. [PDF]

open access: yes, 2016
Prediction performance (area under curve, AUC) of integrative models.
Matthew C. Cowperthwaite (93322)   +3 more
core   +1 more source

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