Results 41 to 50 of about 15,186,604 (295)

Area under Curve (AUC) comparison.

, 2013
Area under Curve (AUC) comparison measuring the ability of recovering the original PPI networks: (a) Y_Tong, (b) H_Bind, (c) H_InAct, (d) F_BioGrid, (e) H_BioGrid using embedding space dimensions of 1 to 20.
Lin Zhu (192179), De-Shuang Huang (396909), Zhu-Hong You (396908), Bing Wang (126120)   +3 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Understanding and application of clinical pharmacokinetic principles using single compartment pharmacokinetic simulation model

National Journal of Physiology, Pharmacy and Pharmacology, 2015
To simplify the principles of pharmacokinetics single compartment model is designed with certain assumptions. Objectives of this model are to understand basic principles of pharmacokinetics, to represent graphically the typical natural log concentration ...
Ashishkumar Zala, ND Kantharia, Aashal B Shah   +2 more
doaj   +1 more source

A relationship between the incremental values of area under the ROC curve and of area under the precision-recall curve

Diagnostic and Prognostic Research, 2021
Background Incremental value (IncV) evaluates the performance change between an existing risk model and a new model. Different IncV metrics do not always agree with each other. For example, compared with a prescribed-dose model, an ovarian-dose model for
Qian M. Zhou, Lu Zhe, Russell J. Brooke, Melissa M. Hudson, Yan Yuan   +4 more
doaj   +1 more source

The estimated optimism-corrected area under the receiver operating characteristic curve (OC-AUC-ROC), for predictive models developed by different machine learning algorithms and feature selection methods.

, 2022
The estimated optimism-corrected area under the receiver operating characteristic curve (OC-AUC-ROC), for predictive models developed by different machine learning algorithms and feature selection methods.
Reza Yaesoubi (207900), Shiying You (12981374), Melanie H. Chitwood (10092869), Kenneth S. Gunasekera (9330249), Jennifer Furin (435179), Valeriu Crudu (704924), Alexandru Codreanu (12119854), Nelly Ciobanu (8263323), Ted Cohen (118302), Joshua L. Warren (3797263)   +9 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Towards non-invasive diagnosis of glioblastoma: identifying metabolic biomarkers in liquid biopsies using a ROC-based approach

Discover Oncology
For over seven decades, the World Health Organization (WHO) has classified central nervous system tumors primarily based on histological criteria. While recent updates have incorporated molecular genetics and histochemistry, this approach still overlooks
Margareth Borges Coutinho Gallo
doaj   +1 more source

A comparative study of diagnostic accuracy in 3026 pleural biopsies and matched pleural effusion cytology with clinical correlation: A methodological issue

Cancer Medicine, 2023
Aim After reading the article by Ivan K. Poon et al. Certain issues regarding the methodology must be addressed. Result First, it was not sufficient using only sensitivity and specificity. Second, we think the receiver operator characteristic curve (ROC)
Wen‐Li Zhang, Xiang Fang, Jian‐Qing Qiu, Tao Cui   +3 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Evaluation of the Methods for Nonlinear Analysis of Heart Rate Variability

Fractal and Fractional, 2023
The dynamics of cardiac signals can be studied using methods for nonlinear analysis of heart rate variability (HRV). The methods that are used in the article to investigate the fractal, multifractal and informational characteristics of the intervals ...
Evgeniya Gospodinova, Penio Lebamovski, Galya Georgieva-Tsaneva, Mariya Negreva   +3 more
doaj   +1 more source