Results 51 to 60 of about 478,663 (300)

Estimation of AUC from 0 to Infinity in Serial Sacrifice Designs. [PDF]

open access: yes, 2005
Nonclinical in vivo animal studies have to be completed before starting clinical studies of the pharmacokinetic behavior of a drug in humans. The drug exposure in animal studies is often measured by the area under the concentration time curve (AUC).
Wolfsegger, Martin J., Jaki, Thomas
core  

Stanford decoding accuracies (CMC AUC % (Cumulative Match Curve Area Under Curve)). [PDF]

open access: yes, 2019
Stanford decoding accuracies (CMC AUC % (Cumulative Match Curve Area Under Curve)).
Barry Devereux (7387685)   +3 more
core   +1 more source

A comparative study of diagnostic accuracy in 3026 pleural biopsies and matched pleural effusion cytology with clinical correlation: A methodological issue

open access: yesCancer Medicine, 2023
Aim After reading the article by Ivan K. Poon et al. Certain issues regarding the methodology must be addressed. Result First, it was not sufficient using only sensitivity and specificity. Second, we think the receiver operator characteristic curve (ROC)
Wen‐Li Zhang   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Receiver Operating Curve indicating the area under curve (AUC) and the discriminative power of risk scores [PDF]

open access: yes, 2016
Receiver Operating Curve indicating the area under curve (AUC) and the discriminative power of risk ...
Satti Vishnupriya (473432)   +4 more
core   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Area under the curve (AUC) and Cmax in glucose tolerance test. [PDF]

open access: yes, 2022
Area under the curve (AUC) and Cmax in glucose tolerance test.
Annalise Di Marco (8611002)   +7 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

ROC curve and the area under the curve (AUC) under different distributional assumptions for the Golub data. [PDF]

open access: yes, 2015
ROC curve and the area under the curve (AUC) under different distributional assumptions for the Golub data.
Mojtaba Ganjali (550736)   +2 more
core   +1 more source

GOLD Classifications, COPD Hospitalization, and All-Cause Mortality in Chronic Obstructive Pulmonary Disease: The HUNT Study

open access: yesInternational Journal of COPD, 2020
Laxmi Bhatta,1 Linda Leivseth,2 Xiao-Mei Mai,1 Anne Hildur Henriksen,3,4 David Carslake,5,6 Yue Chen,7 Arnulf Langhammer,8,* Ben Michael Brumpton4,5,9,* 1Department of Public Health and Nursing, NTNU Norwegian University of Science and Technology ...
Bhatta L   +7 more
doaj  

Home - About - Disclaimer - Privacy