Results 151 to 160 of about 3,042,026 (332)

DRUG REPURPOSING—Overcoming the translational hurdles to clinical use

Pharmacology Research & Perspectives, 2019
Jennifer H. Martin, Nikola A. Bowden
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Comparison of the area under the receiver operating characteristic curve of each mode in cohort A*.

, 2015
Frontzek Karl, Felix Fluri, Jakob Siemerkus, Müller Beat, Achim Gass, Christ-Crain Mirjam, Mira Katan   +6 more
openalex   +2 more sources

A Novel Approach to Model Cumulative Stress: Area Under the s-factor Curve

, 2023
Frank D. Mann, Adolfo G. Cuevas, Sean Clouston, Colin D. Freilich, Zlatan Križan, Sascha Zuber, Linda Wänström, Graciela Muñiz‐Terrera, Patrick O’Keefe, Stacey Voll, Scott Michael Hofer, Joseph Lee Rodgers, Robert F. Krueger   +12 more
openalex   +1 more source

Juvenile dermatomyositis: association between nail fold capillary end row loop- area under the curve- and disease damage indicators. [PDF]

Pediatr Rheumatol Online J, 2023
Khojah A, Morgan G, Klein-Gitelman MS, Pachman LM.   +3 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Area Under Curve by UV Spectrophotometric Method for Determination Albendazole in Bulk

, 2019
Kedar Vikas Dagdu, Manoj Gadhave, Shubham Bhujbal, Bhushan Shrinath   +3 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Sustainable urban development of the π-shaped Curve Area in the Yellow River basin under ecological constraints: A study based on the improved ecological footprint model

, 2022
Yifang Sun, Ninglian Wang
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source