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Methicillin-Resistant <i>Staphylococcus aureus</i> Bacteremia Treated With Vancomycin Calculated by Area-Under-the-Curve in Patients With Elevated Vancomycin Minimum Inhibitory Concentrations. [PDF]
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New England Journal of Medicine, 1999
To the Editor: Our mentoring program at the University of Wisconsin is a time for our third-year medical students to present cases and to discuss their internal-medicine ward experiences.
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To the Editor: Our mentoring program at the University of Wisconsin is a time for our third-year medical students to present cases and to discuss their internal-medicine ward experiences.
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Area under the curve and bioavailability
Pharmacological Research, 2000The Area Under the Curve (AUC) is proportional to the fraction absorbed only if the clearance is constant and the concentration uniform; in all other cases the bioavailability cannot be determined by comparing AUCs.
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Estimation of the area under the ROC curve
Statistics in Medicine, 2002AbstractThe area under the receiver operating characteristic curve is frequently used as a measure for the effectiveness of diagnostic markers. In this paper we discuss and compare estimation procedures for this area. These are based on (i) the Mann–Whitney statistic; (ii) kernel smoothing; (iii) normal assumptions; (iv) empirical transformations to ...
David, Faraggi, Benjamin, Reiser
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Optimization of the Area under the ROC Curve
2008 10th Brazilian Symposium on Neural Networks, 2008In this paper, we propose a new binary classification algorithm (AUCtron), based on gradient descent learning, that directly optimizes AUC (area under the ROC curve). We compare it with a linear classifier and with AUCsplit proposed. The AUCtron algorithm implicitly considers class prior probabilities in the decision criteria.
Cristiano Leite Castro +1 more
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The use of mycophenolate mofetil area under the curve
Current Opinion in Rheumatology, 2021Purpose of review Although mycophenolate mofetil (MMF) has been used successfully to treat a myriad of autoimmune diseases, its complex pharmacokinetics make it difficult to determine the true drug exposure for an individual patient.
Katherine, Chakrabarti +3 more
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