Results 171 to 180 of about 36,753 (202)
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Journal of Pharmacological and Toxicological Methods, 2009
Half life and its derived pharmacokinetic parameters are calculated on an assumption that the terminal phase of drug disposition follows a constant rate of disposition. In reality, this assumption may not necessarily be the case. A new method is needed for analyzing PK parameters if the disposition does not follow a first order PK kinetic.Cumulative ...
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Half life and its derived pharmacokinetic parameters are calculated on an assumption that the terminal phase of drug disposition follows a constant rate of disposition. In reality, this assumption may not necessarily be the case. A new method is needed for analyzing PK parameters if the disposition does not follow a first order PK kinetic.Cumulative ...
exaly +3 more sources
Biopharmaceutics & Drug Disposition, 1997
A limited sampling model has been developed for flunarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (Cmax).
I, Mahmood, J T, Sahlroot
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A limited sampling model has been developed for flunarizine following a 30 mg oral dose in epileptic patients who were receiving phenytoin or carbamazepine or both, to estimate the area under the curve (AUC) and maximum plasma concentration (Cmax).
I, Mahmood, J T, Sahlroot
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2019 2nd International Conference on Advancements in Computational Sciences (ICACS), 2019
Software defect prediction (SDP) models are used to improve effort and testing estimate of software by identifying defective modules beforehand. Precision, recall/true positive rate and false positive rate have been used to evaluate the performance of models.
Zeeshan Ali Rana
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Software defect prediction (SDP) models are used to improve effort and testing estimate of software by identifying defective modules beforehand. Precision, recall/true positive rate and false positive rate have been used to evaluate the performance of models.
Zeeshan Ali Rana
exaly +2 more sources
2009
Area under the concentration/time curve of a substance in pharmacokinetic investigations; describes the extent of the bioavailability of a drug.
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Area under the concentration/time curve of a substance in pharmacokinetic investigations; describes the extent of the bioavailability of a drug.
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Journal of Clinical Oncology, 2019
3024 Background: The dosage of most chemotherapy drugs were performed based on the patients’ body surface area (BSA), including docetaxel (DTX). Previous studies showed that this conventional administration of DTX might cause adverse event, such as neutropenia, and neutropenia was proved to associate with DTX area under curve (AUC).
Yan Zhang +6 more
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3024 Background: The dosage of most chemotherapy drugs were performed based on the patients’ body surface area (BSA), including docetaxel (DTX). Previous studies showed that this conventional administration of DTX might cause adverse event, such as neutropenia, and neutropenia was proved to associate with DTX area under curve (AUC).
Yan Zhang +6 more
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Drug Research, 2015
Statins are widely prescribed medicines and are also available in fixed dose combinations with other drugs to treat several chronic ailments. Given the safety issues associated with statins it may be important to assess feasibility of a single time concentration strategy for prediction of exposure (area under the curve; AUC).
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Statins are widely prescribed medicines and are also available in fixed dose combinations with other drugs to treat several chronic ailments. Given the safety issues associated with statins it may be important to assess feasibility of a single time concentration strategy for prediction of exposure (area under the curve; AUC).
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Research Journal of Pharmacy and Technology, 2016
A simple, rapid, economical, precise and sensitive UV spectrophotometric method has been developed and validated for for the determination of sildenafil citrate in pharmaceutical preparations. The solution of both the drugs and tablet were prepared in water. Area under curve was integrated in the wavelength range of 275.80–303.20 nm.
Rucha Hiremath +4 more
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A simple, rapid, economical, precise and sensitive UV spectrophotometric method has been developed and validated for for the determination of sildenafil citrate in pharmaceutical preparations. The solution of both the drugs and tablet were prepared in water. Area under curve was integrated in the wavelength range of 275.80–303.20 nm.
Rucha Hiremath +4 more
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2011 IEEE GLOBECOM Workshops (GC Wkshps), 2011
In this paper, energy detector's performance is analyzed for the two-hop relay network using the area under the receiver operating characteristic (ROC) curve (AUC) in contrast to the ROC based analysis. AUC provides summary measures for the performance of a system. It provides meaningful performance analysis as it varies only from 0.5 to 1.
Shumon Alam +3 more
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In this paper, energy detector's performance is analyzed for the two-hop relay network using the area under the receiver operating characteristic (ROC) curve (AUC) in contrast to the ROC based analysis. AUC provides summary measures for the performance of a system. It provides meaningful performance analysis as it varies only from 0.5 to 1.
Shumon Alam +3 more
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Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2002
Gastroesophageal reflux disease (GERD) is caused by esophageal exposure to concentrated acid over time. The authors tested the hypothesis that AUC for hydrogen ion activity (H/sup +/) modeled by the power function, predicts mucosal damage and propose that GERD is a two component disease. In 33 continuous 24-h esophageal pH recordings (Hines VA Hospital)
M. Barrientos +3 more
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Gastroesophageal reflux disease (GERD) is caused by esophageal exposure to concentrated acid over time. The authors tested the hypothesis that AUC for hydrogen ion activity (H/sup +/) modeled by the power function, predicts mucosal damage and propose that GERD is a two component disease. In 33 continuous 24-h esophageal pH recordings (Hines VA Hospital)
M. Barrientos +3 more
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2011
Mainz//2011; 56. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 6. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi)
Schneider, M, Frömke, C, Zapf, A
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Mainz//2011; 56. Jahrestagung der Deutschen Gesellschaft für Medizinische Informatik, Biometrie und Epidemiologie (gmds), 6. Jahrestagung der Deutschen Gesellschaft für Epidemiologie (DGEpi)
Schneider, M, Frömke, C, Zapf, A
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