Results 111 to 120 of about 109,317 (301)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Comunidad Indígena Amaicha del Valle: territorio y presente en clave comunitaria
, 2021 En estas páginas se presentan distintos aspectos del presente social y político de la Comunidad Indígena Amaicha del Valle la que, resistiendo con estrategias colectivas desde hace centenares de años, expone su estrecha relación -a partir de prácticas y ...
Ataliva, Víctor Hugo +1 more
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, 1927 "Stamped cover letter of the “Pro-Serrano Committee” titled “File # 11 A. Mr. Gen. Arenas Everardo. Reforma # 337 Puebla, Pue.” Letter from Gen. Francisco Serrano to Gen. Everardo Arenas asking him to go to Puebla and make the pertinent arrangements for
FIDEICOMISO ARCHIVOS PLUTARCO ELIAS CALLES Y FERNANDO TORREBLANCA
core +1 more source
Acta Zoológica LilloanaSe entrega el primer registro de Zelus renardii para Bolivia en base a ejemplares de Cochabamba; y su primera ocurrencia en la provincia argentina de Chubut, con ejemplares de Puerto Madryn.
Sofía Araya-Lobos, Eduardo Faúndez
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2020 Equivocación del Locutor Arenas Botero en el Programa "La Hora Insoportable".Biblioteca Luis Echavarría Villegas, Sala de Patrimonio ...
Correa, Camilo
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
, 1920 Correspondence between Gen. M. Arenas to Gen. Plutarco Elías Calles regarding the military operations. Report of the military operations in the Huasteca Veracruzana. Letter from Carrillo to Gen.
FIDEICOMISO ARCHIVOS PLUTARCO ELÍAS CALLES Y FERNANDO TORREBLANCA
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, 2022 RESUMEN: El presente trabajo parte de la comparación crítico-reflexiva de las experiencias vivenciadas por Adelfa Arenas, docente del área de Educación Artística, y las experiencias personales como estudiante de licenciatura y como docente en los ...
Arenas Montoya, Lina Isabel
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source