Results 131 to 140 of about 109,317 (301)
, 2020 Arenas Bar es nuestra idea de negocio que nos dirige a iniciar una innovación, algo diferente a los sitios convencionales de la ciudad, un lugar donde te olvidarás de tus problemas, estrés y aburrimiento donde basándonos en una investigación acerca de ...
Ramírez Nieves, Karen Yaritza +1 more
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Título tomado de la cubiertaDiscurso que en la solemne función celebrada en la Iglesia de N. Sra. de Atocha el día 1º de enero del presente año con motivo de la instalación en España de la Asociación de la Santa Infancia pronunció ...
Arenas, Pedro, m. 1864
core
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2013 El siguiente trabajo permite describir los procesos realizados en las áreas funcionales de recursos humanos, financiera y de mercadeo de la empresa Ríos & Arenas S.A ...
Cardona Restrepo, Sara
core
Paratexto, texto e intertexto de El mundo alucinante, de Reinaldo Arenas [PDF]
, 2012 "Lo que pretendo con este trabajo es explorar desde otro punto de vista "EL mundo alucinante: paratexto, texto e intertexto". El corpues con el que trabajé serán las dos ediciones más importantes de la novela: la de Diógenes (1969), que se público cuando
DAYNA DÍAZ URIBE
core
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source