Results 71 to 80 of about 109,317 (301)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
CD21+CD11c+ B cells predicting handgrip strength decline in older adults
Frontiers in AgingBackgroundPreserving physical function is central to healthy aging, and declines in handgrip strength are strong predictors of frailty, disability, and mortality.
Diego Mabe-Castro +7 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Gayana: Botanica, 2023 In recent decades the fluence of ultraviolet-B (UV-B) radiation striking the ground has increased as a consequence of ozone depletion at southern latitudes. This phenomenon has sparked much interest in unravelling how plants acclimate to this condition.
Roberto Niculcar +2 more
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
, 2020 The third year of Human Arenas presents number of developmental tasks. After 2 years of experimentation, Human Arenas is becoming an acknowledged interdisciplinary space for intellectual bravery.
Marsico Giuseppina
core +1 more source
Temporal Stability of Bacterial Communities in Antarctic Sponges
Frontiers in Microbiology, 2019 Marine sponges host dense, diverse, and species-specific microbial communities around the globe; however, most of the current knowledge is restricted to species from tropical and temperate waters.
César A. Cárdenas +4 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
, 2016 El doctor Juan Sebastián Cano Arenas, médico especializado en dolor y cuidado paliativo nos habla de esta especialidad médica y área de la Medicina que se encarga de las atenciones, cuidados y tratamientos médicos y tratamientos farmacológicos que se dan
Cano Arenas, Juan Sebastián
core