Results 61 to 70 of about 109,317 (301)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Entrevista a José Arenas López
, 2019 Entrevistas Jornada MAKER STREAHMEntrevista a José Arenas ...
Arenas López, José
core
The appearance of «intelligence» in self-propelled bots
Вісник Харківського національного університету імені В.Н. Каразіна. Серія: Математичне моделювання, інформаційні технології, автоматизовані системи управлінняRelevance. Nowadays, the study of the behavior and properties of active matter, which corresponds to the collective behavior of self-moving elements, is very promising field of research. Active matter is widespread in nature and is used in various modern
Дмитро Образцов +1 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Carme Arenas a les lliçons de la Càtedra
, 2018 Aquest any la convidada a les Lliçons de la Càtedra de Patrimoni Literari Maria Àngels Anglada - Carles Fages de Climent, ha estat la Sra. Carme Arenas, traductora, escriptora, editora i presidenta del PEN català, per explicar la seva experiència ...
Arenas, Carme
core
Frontiers in PsychiatryBackgroundPopulations living at high southern latitudes are under-represented in aging and psychophysiology research, despite distinctive environmental stressors (long winters, marked seasonality, isolation). Objectives: To test associations between SPS,
Diego Baeza +8 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Investigaciones Geográficas, 2014 Este trabajo investiga la relación entre la mineralogía de sedimentos fluviales, su área fuente y el clima, en un tramo del río Portuguesa en los llanos centro-occidentales venezolanos.
Orlando José González Clemente +3 more
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2019 After the first year of its existence, Human Arenas is celebrating quite impressive results obtained during 2018. The core of the journal’s editorial policy is the innovative concept of “cultivation rate,” which is challenging a too rigid and short ...
Giuseppina Marsico
core +1 more source