Results 121 to 130 of about 9,646 (208)

O-Fucosyltransferase SPINDLY attenuates auxin-induced fruit growth by inhibiting ARF6/8-coactivator mediator complex interaction in Arabidopsis

Nature Communications
The phytohormone auxin plays a pivotal role in promoting fruit initiation and growth upon fertilization in flowering plants. Upregulation of auxin signaling by genetic mutations or exogenous auxin treatment can induce seedless fruit formation from ...
Yan Wang, Seamus Kelley, Rodolfo Zentella, Jianhong Hu, Hua Wei, Lei Wang, Jeffrey Shabanowitz, Donald F. Hunt, Tai-ping Sun   +8 more
doaj   +1 more source

miR-28–3p suppresses gastric cancer growth and EMT-driven metastasis by targeting the ARF6/Hedgehog axis

Molecular and Cellular Probes
Gastric cancer (GC), among the most prevalent malignant tumors globally, demonstrates a rapid metastasis rate leading to high mortality. While microRNAs (miRNAs) have been recognized as critical regulators of tumor progression, the specific role of miR ...
Hua Ji, Sicheng Liu, Libo Yang, Yunhua Wu, Huanqing Zhang, Xueqing Liu, Linhai Li, Lihua Li   +7 more
doaj   +1 more source

Abstract 1357: The small GTPase Arf6 potentiates melanoma metastasis by activating Akt

, 2017
Arf6 is a member of the Ras-superfamily of small GTPases and controls membrane trafficking and cytoskeletal remodeling, functioning mainly in endocytosis pathways at the cell periphery.
Dean Y. Li, Allie H. Grossmann, Sheri Holmen, Lehi Acosta, Jae H. Yoo, Shannon J. Odelberg, Aaron Rogers   +6 more
core   +1 more source

Characterizing new mutations of ARF6 and ARF8 in Arabidopsis thaliana [PDF]

Auxin is a key phytohormone that regulates various developmental and maturation processes in plants. Intracellular auxin induces ARF (Auxin Response Factor) activation through the turnover of Aux/IAA (Auxin/Indole-3-Acetic Acid) repressors that otherwise
Ramanujam, Rashmi
core   +1 more source

ADP-RIBOSYLATION FACTOR 6 (ARF6) REGULATES INTEGRIN αIIbβ3 TRAFFICKING, PLATELET SPREADING, AND CLOT RETRACTION [PDF]

, 2015
Endocytic trafficking of platelet surface receptors plays a role in the accumulation of granule cargo (i.e. fibrinogen and VEGF) and thus could contribute to hemostasis, angiogenesis, or inflammation.
Huang, Yunjie
core  

ARF6 Gene [PDF]

, 2020
openaire   +1 more source

ADAP1 and Arf6 Mediate Regulated Secretory Trafficing in Neurosecretory Cells and Neurons [PDF]

, 2013
ADP ribosylation factor 6 (Arf6) is a member of the Arf family of small GTPases known to function in vesicular membrane trafficking and cytoskeletal organization. Arf6 cycles between its GTP and GDP bound states, facilitated by GTP exchange factors (GEFs)
Ewell, Sharday
core  

Macropinocytosis of Amyloid Precursor Protein Is Regulated by the Recruitment and Activity of Fe65, Arf6 and Rho GTPases. [PDF]

Cells
Krupa JM, Medapati MR, Naqvi AM, Hallam RD, Tsang AR, Seah C, Whitehead SN, Pasternak SH.   +7 more
europepmc   +1 more source

SNAI1 ablation alters integrin-mediated adhesion and endocytic fate. [PDF]

Cell Death Dis
Tsirigoti C, Ali MM, Morén A, Johansson S, Munson MJ, Heldin CH, Moustakas A, Rodrigues-Junior DM.   +7 more
europepmc   +1 more source

Protocol for detecting protein recruitment to clathrin structures in cultured cells. [PDF]

STAR Protoc
Orofiamma LA, Antonescu CN.
europepmc   +1 more source