Results 101 to 110 of about 9,646 (208)
The Effect of MicroRNA-31 on the small GTPase Arf6 and the role of Arf6 in Early Embryogenesis
, 2013 microRNAs (miRNAs) are small, non-coding mRNAs that repress protein translation and/or mRNA degradation. Our lab has demonstrated that microRNAs are vital for early development. microRNA-31 is one of the most abundant miRNAs in the sea urchin embryo, and
Dumas, Megan
core
Arf6-T27N increases hERG current density.
, 2013 Assessment of dominant negative Arf6, cdc42 and µ2 constructs on hERG current density. (A) Current-voltage relationships of hERG channels co-expressed with Arf6-T27N-eGFP, eGFP-cdc42-T17N or µ2-D176A/W421A in HEK-MSR cells; representative current ...
Rucha Karnik (504688) +6 more
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PLoS Biology, 2006 Fcgamma receptor (FcgammaR)-mediated phagocytosis of IgG-coated particles is regulated by 3'-phosphoinositides (3'PIs) and several classes of small GTPases, including ARF6 from the ADP Ribosylation Factor subfamily.
Peter Beemiller +2 more
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ARF6-dependent regulation of P2Y receptor traffic and function in human platelets.
PLoS ONE, 2012 Adenosine diphosphate (ADP) is a critical regulator of platelet activation, mediating its actions through two G protein-coupled receptors, the P2Y(1) and P2Y(12) purinoceptors. Recently, we demonstrated that P2Y(1) and P2Y(12) purinoceptor activities are
Venkateswarlu Kanamarlapudi +4 more
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Effects of GEP100/Arf6 on EGF-induced cell migration.
, 2012 (A) EGF induces activation of Arf6. Serum-starved cell monolayers were treated with 10 ng/mL EGF for the indicated times. Cellular lysates were assayed for active Arf6 by pulldown assays as described in ‘Materials and methods’. The data were mean ± SD of
Xiang Lu (158823) +8 more
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Measurement of ARF6-CFP and ARF1-CFP Activation at Phagosomes
, 2013 FRET microscopic measurement of ARF6-CFP and ARF1-CFP activation during phagocytosis. (A, C, and E) Phase contrast and ED images of phagocytic events from macrophages co-expressing ARF6-CFP and YFP-NGAT, ARF1-CFP and YFP-NGAT, or ARF6-CFP and
Adam D Hoppe (57946) +2 more
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Effects of Arf6 downregulation on biological characteristics of human prostate cancer cells [PDF]
International Brazilian Journal of UrologyObjective To evaluate the effects of Arf6 downregulation on human prostate cancer cells. Materials and Methods The effects of Arf6 downregulation on cell proliferation, migration, invasion and apoptosis were assessed by MTT, BrdU, scratch, Transwell ...
Haiming Lei +3 more
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ARF6 GTPase controls bacterial invasion by actin remodelling.
, 2005 The obligate intracellular bacterium Chlamydia penetrates the host epithelial cell by inducing cytoskeleton and membrane rearrangements reminiscent of phagocytosis.
Chavrier, Philippe +5 more
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ITSN1 interacts with components of the Arf6 GTPase pathways.
, 2012 A. ITSN1 interacts with Arf6 as well as its effector Arfaptin2. BiFC was used to analyze the interaction of ITSN1S with components of the Arf6 pathway. VN-ITSN1-S was co-expressed in COS cells with VC-Arf6 (top panels), VC-Arfaptin2 (middle panels), or ...
Katy A. Wong (168298) +9 more
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miR-145-5p Inhibits HER2-Positive Breast Cancer Cells via Targeting ARF6
International Journal of General MedicineLixian Yang,1 Wei Dang,2 Fanting Kong,1 Xuan Zhang,1 Lei Zheng,1 Lining Jia,1 Xiaowei Li,1 Na Lu1 1Department of Breast Surgery, Xingtai People’s Hospital, Xingtai, Hebei Province, 054000, People’s Republic of China; 2Medical Research Center, Xingtai ...
Yang L +7 more
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