Results 1 to 10 of about 50 (42)

A Higher Frequency Administration of the Nontoxic Cycloartane-Type Triterpene Argentatin A Improved Its Anti-Tumor Activity [PDF]

Molecules, 2020
Parthenium argentatum (Gray), commonly known as guayule, has been used to obtain natural rubber since the beginning of the 20th century. Additionally, the so called “resin” is a waste product derived from the industrial process.
Nadia Judith Jacobo-Herrera, Leticia Rocha-Zavaleta, Alejandro Zentella-Dehesa   +2 more
exaly   +4 more sources

Argentatin B Inhibits Proliferation of Prostate and Colon Cancer Cells by Inducing Cell Senescence [PDF]

Molecules, 2015
Argentatin B has been shown to inhibit the growth of colon HCT-15, and prostate PC-3 cancer cells. However, the mechanism by which argentatin B inhibits cell proliferation is still unknown.
Leticia Rocha-Zavaleta, Mariano Martínez-Vázquez, Brechú-Franco Alicia Enriqueta   +2 more
exaly   +4 more sources

Argentatin Content in Guayule Leaves (Parthenium argentatum A. Gray) [PDF]

Plants, 2023
Approximately one-third of the waste biomass from the cultivation of guayule (Parthenium argentatum A. Gray) for natural rubber production is leaf tissue; however, whether it can be valorized is not known.
María Mercedes García-Martínez, Beatriz Gallego, Guayente Latorre, María Engracia Carrión, Miguel Ángel De la Cruz-Morcillo, Amaya Zalacain, Manuel Carmona   +6 more
doaj   +2 more sources

Biopesticide Activity of Guayule Resin [PDF]

Plants, 2022
The extensive use of synthetic pesticides has created considerable concern for both human health and the environment, which has prompted the search for safer alternatives, such as the resin of guayule (Parthenium argentatum).
Guayente Latorre, María Mercedes García-Martínez, María Martín-Bejerano, Luis F. Julio, Amaya Zalacain, María Engracia Carrión, Manuel Carmona   +6 more
doaj   +2 more sources

Synergistic Potential of Argentatins A and B to Improve 5-Fluorouracil Cytotoxicity in Colorectal Cancer Cell Models. [PDF]

J Cell Mol Med
ABSTRACT Colorectal cancer is the third most commonly diagnosed cancer worldwide and the second most common cause of cancer‐related death in both men and women. Although a number of treatments are available to combat this malignancy, the antimetabolite 5‐fluorouracil has been the cornerstone of therapy since its synthesis in the 1950s.
Sánchez-Olivares P, Silva-Nolasco AM, de la Cruz-Morcillo MA, García-Martínez MM, Pinedo-Serrano A, Carmona M, Galán-Moya EM.   +6 more
europepmc   +2 more sources

Differential anti-cancer effects of argentatin A and B: antimigratory, antiangiogenic, and long-term resistance induction

Industrial Crops and Products
Argentatin A and B are naturally occurring triterpenes isolated from Parthenium argentatum A. Gray (guayule) and are recognized for their cytotoxic activity; however, their functional and molecular effects following prolonged exposure remain poorly ...
BEATRIZ G Galvez, Aniela M Silva-Nolasco, Manuel Carmona   +2 more
exaly   +3 more sources

Argentatins exert anti-adipogenic and anti-inflammatory effects on 3T3-L1 cells under inflammatory conditions

Industrial Crops and Products
Argentatins are secondary metabolites isolated from the resin of guayule (Parthenium argentatum). Two specific compounds, argentatin A (aA) and argentatin B (aB), possess beneficial bioactivities.
Silvia García-Dávila, Miguel Ángel de la Cruz-Morcillo, Cristina Garnés-García, Carmen Cifuentes, Beatriz G. Gálvez, Manuel Carmona, Sílvia Llorens   +6 more
doaj   +1 more source

Synthesis of Cycloartan‐16β‐ol from 16β 24R‐Epoxy‐Cycloartane and Their Cytotoxicity Evaluation Against Human Cancer Cell Lines

Chemistry &Biodiversity, Volume 21, Issue 5, May 2024.
Abstract It was found that Argentatins A and B triterpenoids make up approximately 20–30 % of the waste resin produced from the industrial processes to isolate rubber from P. argentatum. We have developed an efficient protocol for synthesizing cycloartane‐16β‐ol derivatives by opening the oxepane ring of argentatin B acetate (2) with BF3‐OEt2. Although
Atzin Hernández‐Flandes, Simón Hernández‐Ortega, Teresa Ramírez‐Apan, Leticia Rocha‐Zavaleta, Noemi Silva‐Jimenez, Mariano Martínez‐Vázquez   +5 more
wiley   +1 more source

Argentatin C Analogues with Potential Antinociceptive Activity and Other Triterpenoid Constituents from the Aerial Parts of <i>Parthenium incanum</i>. [PDF]

ACS Omega, 2023
Xu YM, Wijeratne EMK, Calderon-Rivera A, Loya-López S, Perez-Miller S, Khanna R, Gunatilaka AAL.   +6 more
europepmc   +1 more source

Composition of Guayule (Parthenium argentatum Gray) resin. [PDF]

Sci Rep, 2023
Rousset A, Ginies C, Chevallier O, Martinez-Vazquez M, Amor A, Dorget M, Chemat F, Perino S.   +7 more
europepmc   +1 more source