Results 11 to 20 of about 85 (58)

Immunomodulatory activity of argentatins A and B isolated from guayule. [PDF]

PLoS One
Argentatins are secondary metabolites synthesized by guayule (Parthenium argentatum A. Gray) with numerous potential medical applications. In addition to inhibiting insect growth, they are endowed with several pharmacological properties including antimicrobial and antitumorigenic activity. However, their potential as immunomodulators remains unexplored.
Silva-Nolasco AM, de la Cruz-Morcillo MA, García-Martínez MM, Zalacain A, Gálvez BG, Carmona M.   +5 more
europepmc   +6 more sources

Semi-Synthesis and Cytotoxicity Evaluation of Pyrimidine, Thiazole, and Indole Analogues of Argentatins A–C from Guayule (Parthenium Argentatum) Resin [PDF]

Medicinal Chemistry Research, 2021
Abstract Argentatins A–C (1–3), the major cycloartane-type triterpenoids of guayule resin, a byproduct of commercial rubber production, were converted into their pyrimidine (7–12), thiazole (13–15), and indole (16–18) analogues by a molecular hybridization approach.
Chandrashekhar Madasu, Ya-Ming Xu, E. M. Kithsiri Wijeratne, Manping X. Liu, István Molnár, A. A. Leslie Gunatilaka   +5 more
openaire   +3 more sources

Microbial transformation of argentatins by Cunninghamella elegans

Biocatalysis and Biotransformation
Microbial biotransformation of argentatin A (1), isoargentatin A (2) and argentatin B (3), the cycloartane- and lanostane-type triterpenoid constituents of guayule (Parthenium argentatum) resin, with Cunninghamella elegans ATCC 9245-A0 afforded eight new metabolites 4–11.
Zhong, Weimao, Xu, Ya ming, Wijeratne, E. M.Kithsiri, Inácio, Marielle C., Molnár, István, Gunatilaka, A. A.Leslie   +5 more
openaire   +1 more source

Overexpression of tocopherol biosynthesis genes in guayule (Parthenium argentatum) reduces rubber, resin and argentatins content in stem and leaf tissues

Phytochemistry
Natural rubber produced in stems of the guayule plant (Parthenium argentatum) is susceptible to post-harvest degradation from microbial or thermo-oxidative processes, especially once stems are chipped. As a result, the time from harvest to extraction must be minimized to recover high quality rubber, especially in warm summer months.
Grisel Ponciano, Niu Dong, Chen Dong, Andrew Breksa, Ana Vilches, Maha T. Abutokaikah, Colleen McMahan, F. Omar Holguin   +7 more
openaire   +2 more sources

Cycloartane- and Lanostane-Type Triterpenoids from the Resin of Parthenium argentatum AZ-2, a Byproduct of Guayule Rubber Production. [PDF]

ACS Omega, 2021
Xu YM, Madasu C, Liu MX, Wijeratne EMK, Dierig D, White B, Molnár I, Gunatilaka AAL.   +7 more
europepmc   +1 more source

Plant-derived natural products targeting ion channels for pain. [PDF]

Neurobiol Pain, 2023
Goyal S, Goyal S, Goins AE, Alles SRA.
europepmc   +1 more source

Guayule (Parthenium argentatum A. Gray), a Renewable Resource for Natural Polyisoprene and Resin: Composition, Processes and Applications. [PDF]

Molecules, 2021
Rousset A, Amor A, Punvichai T, Perino S, Palu S, Dorget M, Pioch D, Chemat F.   +7 more
europepmc   +1 more source

Flavonoid Composition and Antioxidant Activity of Tragia volubilis L. Methanolic Extract. [PDF]

Plants (Basel), 2023
Romero-Benavides JC, Atiencie-Valarezo NC, Duarte-Casar R.   +2 more
europepmc   +1 more source

Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective. [PDF]

ACS Omega, 2023
Chahal S, Rani P, Kiran, Sindhu J, Joshi G, Ganesan A, Kalyaanamoorthy S, Mayank, Kumar P, Singh R, Negi A.   +10 more
europepmc   +1 more source

Effect of Argentatins on Adipogenensis in Inflamatory Conditions

Obesity is a pathology of growing importance in the world due to its high prevalence and its association with numerous comorbidities, including cardiovascular disease, Type 2 diabetes and certain types of cancer. It is characterized by excess body fat resulting from an imbalance between caloric intake and energy expenditure.
Girón López, Lucía, Cruz Morcillo, Miguel Ángel de la, Carmona Delgado, Manuel, Llorens Folgado, Silvia   +3 more
openaire   +1 more source