A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang+17 more
wiley +1 more source
Saturation kinetics and specificity of transporters for L-arginine and asymmetric dimethylarginine (ADMA) at the blood-brain and blood-CSF barriers. [PDF]
Fidanboylu M, Thomas SA.
europepmc +1 more source
Metabolism of Exogenous Arginine and Glucose by Starved Streptococcus Lactis in Relation to Survival
Thomas Thymann, Richard D. Batt
openalex +1 more source
Arginine: Its pKa value revisited
C. A. Fitch+4 more
semanticscholar +1 more source
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei+11 more
wiley +1 more source
Optimization of Medium Composition for High Cell Density Culture of Bifidobacterium longum HSBL001 Using Response Surface Methodology. [PDF]
Cheng H+9 more
europepmc +1 more source
Alterations in arginine metabolism and β‐hydroxybutyrylation (Kbhb) modifications play a critical role in tumor progression. This study reveals valuable insights into arginine metabolism reprogramming involving the ARG1‐Kbhb/P300/SLC3A2 signaling axis and uncovers an effective therapy combining BHB with ARG1 inhibitor through conventional enzymatic and
Chuman Lin+6 more
wiley +1 more source
Safety and efficacy of a feed additive consisting of l-arginine produced with <i>Corynebacterium glutamicum</i>KCCM 80393 for all animal species (Daesang Europe BV). [PDF]
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)+21 more
europepmc +1 more source
ID1 is regulated by E3 ligase TRIM21, which adds non‐degradative K11‐linked ubiquitin at Lys91, disrupting ID1‐TCF12 binding and freeing TCF12 to upregulate copper transporter SLC31A1. Enhanced SLC31A1 elevates intracellular copper, triggers cuproptosis, and inhibits ESCC growth.
Lei Li+6 more
wiley +1 more source
Reply to Trexler, E.T. Common Errors in Sports Nutrition Meta-Analyses Lead to Distortion of Pooled Effect Estimates. Comment on "Viribay et al. Effects of Arginine Supplementation on Athletic Performance Based on Energy Metabolism: A Systematic Review and Meta-Analysis. <i>Nutrients</i> 2020, <i>12</i>, 1300". [PDF]
Viribay A+3 more
europepmc +1 more source