L-arginine from elder human mesenchymal stem cells induces angiogenesis and enhances therapeutic effects on ischemic heart diseases. [PDF]
Li JZ+8 more
europepmc +1 more source
Longitudinal Metabolomics in Amyotrophic Lateral Sclerosis Implicates Impaired Lipid Metabolism
Objective Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by altered metabolome and energy homeostasis, manifesting with body mass index changes and hypermetabolism—both prognostic of disease progression and survival.
Kai Guo+7 more
wiley +1 more source
Metabolic correlations between kidney and eye in a mouse model of oxygen-induced retinopathy and retinopathy of prematurity. [PDF]
Yang Y+11 more
europepmc +1 more source
Objective Gain‐of‐function (GoF) variants in KCNT1 encoding for potassium channels are associated with different epilepsy phenotypes, including epilepsy of infancy with migrating focal seizures (EIMFS), other early infantile developmental and epileptic encephalopathies, and focal epilepsy.
Marina Trivisano+13 more
wiley +1 more source
L-Arginine Activates the Neuregulin-1/ErbB Receptor Signaling Pathway and Increases Utrophin mRNA Levels in C2C12 Cells. [PDF]
Tapia G+6 more
europepmc +1 more source
Advances on Albumin‐Based Carriers for Anticancer Drug Delivery
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou+4 more
wiley +1 more source
Citrulline Plus Arginine Induces an Angiogenic Response and Increases Permeability in Retinal Endothelial Cells via Nitric Oxide Production. [PDF]
Warden C, Zubieta D, Brantley MA.
europepmc +1 more source
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli+3 more
wiley +1 more source
The Potential Mechanisms of <i>Althaea rosea</i> (Linn.) Cavan. Flower in Alleviating Tetrodotoxin Poisoning: An Integrated Metabolomics, Network Pharmacology and Experimental Validation. [PDF]
Zheng R, Wu Y, Huang L, Zeng F, Huang L.
europepmc +1 more source
In diesem Forschungsartikel wird die Herstellung und systematische Untersuchung neuartiger, zwitterionischer Dipeptid‐funktionalisierter Nanodiamanten zur Gewährleistung der kolloidalen Stabilität über einen breiten pH‐Bereich und in biologischen Medien vorgestellt.
Elisabeth Mayerhoefer+5 more
wiley +1 more source