Results 331 to 340 of about 793,177 (388)

Longitudinal Metabolomics in Amyotrophic Lateral Sclerosis Implicates Impaired Lipid Metabolism

open access: yesAnnals of Neurology, EarlyView.
Objective Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by altered metabolome and energy homeostasis, manifesting with body mass index changes and hypermetabolism—both prognostic of disease progression and survival.
Kai Guo   +7 more
wiley   +1 more source

Metabolic correlations between kidney and eye in a mouse model of oxygen-induced retinopathy and retinopathy of prematurity. [PDF]

open access: yesBMJ Open Ophthalmol
Yang Y   +11 more
europepmc   +1 more source

Fluoxetine Treatment in Epilepsy of Infancy with Migrating Focal Seizures Due to KCNT1 Variants: An Open Label Study

open access: yesAnnals of Neurology, EarlyView.
Objective Gain‐of‐function (GoF) variants in KCNT1 encoding for potassium channels are associated with different epilepsy phenotypes, including epilepsy of infancy with migrating focal seizures (EIMFS), other early infantile developmental and epileptic encephalopathies, and focal epilepsy.
Marina Trivisano   +13 more
wiley   +1 more source

Advances on Albumin‐Based Carriers for Anticancer Drug Delivery

open access: yesAdvanced NanoBiomed Research, EarlyView.
This study systematically classifies the drug delivery modes of albumin by examining the characteristics of its surface‐active groups and internal binding sites. It provides an in‐depth analysis of various drug delivery strategies and their corresponding targeting mechanisms.
Ruoli Zhou   +4 more
wiley   +1 more source

Graphene Oxide‐Based Gene Modulation in Preferential Elimination of Lung Cancer Cells in a 3D Tumor Microenvironment Model

open access: yesAdvanced NanoBiomed Research, EarlyView.
Chemically modified graphene oxide nanocarriers provide a targeted lung cancer gene therapy platform. In a 3D tumor microenvironment model, these nanocarriers deliver therapeutic genes, regulate immune markers, and induce apoptosis in cancer cells. Combined gene delivery enhances cancer cell elimination, demonstrating the potential of this approach for
Francesca Grilli   +3 more
wiley   +1 more source

Zwitterionische Dipeptid‐Oberflächenfunktionalisierung von Detonationsnanodiamant zur Optimierung der Partikeleigenschaften in biologischen Systemen

open access: yesAngewandte Chemie, EarlyView.
In diesem Forschungsartikel wird die Herstellung und systematische Untersuchung neuartiger, zwitterionischer Dipeptid‐funktionalisierter Nanodiamanten zur Gewährleistung der kolloidalen Stabilität über einen breiten pH‐Bereich und in biologischen Medien vorgestellt.
Elisabeth Mayerhoefer   +5 more
wiley   +1 more source

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