Results 331 to 340 of about 753,681 (356)

Arginine metabolism in myeloid cells in health and disease. [PDF]

open access: yesSemin Immunopathol
Karadima E, Chavakis T, Alexaki VI.
europepmc   +1 more source

Biaryl Phosphates and Phosphonates as Selective Inhibitors of the Transcription Factor STAT4

open access: yesAngewandte Chemie, EarlyView.
The transcription factor STAT4 is a therapeutic target for autoimmune diseases. Here, para‐biaryl phosphates and phosphonates are presented as the first small‐molecule inhibitors of STAT4. The phosphonate Stafori‐1 selectively stabilizes STAT4 against thermal denaturation in cell lysates, and its cell‐permeable prodrug Pomstafori‐1 selectively inhibits
Nadiya Brovchenko   +7 more
wiley   +1 more source

Synthetic High‐Throughput Microarrays of Peptidoglycan Fragments as a Novel Sero‐Diagnostic Tool for Patient Antibody Profiling

open access: yesAngewandte Chemie International Edition, EarlyView.
Using a novel on‐chip synthesis technology, microarrays of peptidoglycan fragments were generated comprising 864 variants derived from Gram‐positive and Gram‐negative bacteria. These were used to map monoclonal antibody specificity and to screen samples from patients with the autoimmune disease epidermolysis bullosa, revealing distinct antibody ...
Alexandra Tsouka   +12 more
wiley   +1 more source

L-arginine ameliorates hypertension and cardiac mitochondrial abnormalities but not cardiac injury in male metabolic syndrome rats. [PDF]

open access: yesPhysiol Rep
Tagami K   +11 more
europepmc   +1 more source

Elevated Plasma Level of Arginine and Its Metabolites at Labor Among Women With Preeclampsia: A Prospective Cohort Study. [PDF]

open access: yesAm J Hypertens
Akhter T   +6 more
europepmc   +1 more source

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