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Metabolomic reprogramming of the tumor microenvironment by dual arginase inhibitor OATD-02 boosts anticancer immunity. [PDF]

open access: yesSci Rep
Grzybowski MM   +16 more
europepmc   +1 more source
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Arginine-Mediated RNA Recognition: the Arginine Fork

Science, 1991
Short peptides that contain the basic region of the HIV-1 Tat protein bind specifically to a bulged region in TAR RNA. A peptide that contained nine arginines (R 9 ) also bound specifically to TAR, and a mutant Tat protein that contained R 9 was fully active for transactivation.
Sara Biancalana   +4 more
openaire   +3 more sources

Biosynthesis of Arginine and Polyamines

EcoSal Plus, 2004
Early investigations on arginine biosynthesis brought to light basic features of metabolic regulation. The most significant advances of the last 10 to 15 years concern the arginine repressor, its structure and mode of action in bothE. coliandSalmonella typhimurium, the sequence analysis of allargstructural genes inE.
Charlier, Daniel, Glansdorff, Nicolas
openaire   +4 more sources

Determination of Arginine

Nature, 1956
THE orange-red colour produced by arginine and other mono-alkyl guanidines in the presence of α-naphthol and hypochlorites or hypobromites1 would probably be more widely used in analysis, were existing methods capable of a stable calibration or more reproducible.
openaire   +3 more sources

Arginine and Asthma

2013
Recent studies suggest that alterations of the arginine metabolome and a dysregulation of nitric oxide (NO) homeostasis play a role in the pathogenesis of asthma. L-Arginine, a semi-essential amino acid, is a common substrate for both the arginases and NO synthase (NOS) enzyme families.
openaire   +3 more sources

Multi-Faceted Arginine: Mechanism of the Effects of Arginine on Protein

Current Protein & Peptide Science, 2014
Arginine is widely used in such applications as protein refolding, solubilization of proteins and small molecules, protein and small molecule formulation, column chromatography and viral inactivation as summarized in this review. What makes arginine effective in these applications is largely based on its ability to suppress protein-protein interactions
Yoshiko Kita, Tsutomu Arakawa
openaire   +2 more sources

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