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Protein arginine methylation: from enigmatic functions to therapeutic targeting
Nature reviews. Drug discovery, 2021Qin Wu +3 more
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Effect of arginine and canavanine on arginine messenger RNA synthesis
Biochemical and Biophysical Research Communications, 1971Summary The level of messenger RNA for the arg ECBH gene cluster in Escherichia coli was determined by hybridization of 3 H-pulse-labeled RNA with DNA from 80darg. L-Arginine repressed the level of hybridizable message 7 to 24 fold lower than that observed in arginine-deprived cells.
Palmer Rogers +3 more
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Transport of L-Arginine in Arginine-Deprived Endothelial Cells
Biochemical and Biophysical Research Communications, 1995In vascular endothelium, L-arginine (ARG) plays a crucial role as a substrate for various metabolic pathways, one of which is the synthesis of bioregulatory nitric oxide. Transport of ARG across the cell membrane determines intracellular substrate availability.
S. Zink +3 more
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Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate.
Biochemistry, 1988Previous studies have shown that murine macrophages immunostimulated with interferon gamma and Escherichia coli lipopolysaccharide synthesize NO2-, NO3-, and citrulline from L-arginine by oxidation of one of the two chemically equivalent guanido ...
M. Marletta +4 more
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The lung in the balance: arginine, methylated arginines, and nitric oxide
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2007the lung is a major source of nitric oxide (NO), be it from nitric oxide synthase (NOS) III in the endothelium of the vast pulmonary circulation, NOS II in the epithelium of the large surface area of the airways, or NOS I in the nonadrenergic noncholinergic nerves ([6][1]).
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Vascular endothelial cells synthesize nitric oxide from L-arginine
Nature, 1988R. Palmer, D. Ashton, S. Moncada
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Measurement of Arginine Vasopressin
2013Arginine vasopressin (AVP) is a peptide hormone synthesised in the hypothalamus and secreted from nerve terminals within the posterior pituitary gland. Secretion is primarily under osmoregulatory control and levels rise in plasma in response to a body water deficit and are suppressed in response to water overload.
Nadia El-Farhan +2 more
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The regulation, functions and clinical relevance of arginine methylation
Nature reviews. Molecular cell biology, 2019E. Guccione, S. Richard
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The Journal of Nutrition, 1985
Studies of ammonia intoxication, orotic acid excretion and L-amino acid feeding regimens have provided new insights into the biological function of arginine. Recent data in near adults of carnivorous species raise doubts about the widely held view that arginine is needed in the diet only for optimum growth and that adults of mammalian species meet ...
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Studies of ammonia intoxication, orotic acid excretion and L-amino acid feeding regimens have provided new insights into the biological function of arginine. Recent data in near adults of carnivorous species raise doubts about the widely held view that arginine is needed in the diet only for optimum growth and that adults of mammalian species meet ...
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Arginine Methylation: The Coming of Age.
Molecules and Cells, 2017Roméo S. Blanc, S. Richard
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