Results 361 to 370 of about 843,121 (388)

Arginine and Asthma

2013
Recent studies suggest that alterations of the arginine metabolome and a dysregulation of nitric oxide (NO) homeostasis play a role in the pathogenesis of asthma. L-Arginine, a semi-essential amino acid, is a common substrate for both the arginases and NO synthase (NOS) enzyme families.
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Multi-Faceted Arginine: Mechanism of the Effects of Arginine on Protein

Current Protein & Peptide Science, 2014
Arginine is widely used in such applications as protein refolding, solubilization of proteins and small molecules, protein and small molecule formulation, column chromatography and viral inactivation as summarized in this review. What makes arginine effective in these applications is largely based on its ability to suppress protein-protein interactions
Yoshiko Kita, Tsutomu Arakawa
openaire   +2 more sources

Protein arginine methylation: from enigmatic functions to therapeutic targeting

Nature reviews. Drug discovery, 2021
Qin Wu, M. Schapira, C. Arrowsmith, D. Barsyte-Lovejoy   +3 more
semanticscholar   +1 more source

Effect of arginine and canavanine on arginine messenger RNA synthesis

Biochemical and Biophysical Research Communications, 1971
Summary The level of messenger RNA for the arg ECBH gene cluster in Escherichia coli was determined by hybridization of 3 H-pulse-labeled RNA with DNA from 80darg. L-Arginine repressed the level of hybridizable message 7 to 24 fold lower than that observed in arginine-deprived cells.
Palmer Rogers, Edward Arfman, R. A. Krzyzek, Ted M. Kaden   +3 more
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Transport of L-Arginine in Arginine-Deprived Endothelial Cells

Biochemical and Biophysical Research Communications, 1995
In vascular endothelium, L-arginine (ARG) plays a crucial role as a substrate for various metabolic pathways, one of which is the synthesis of bioregulatory nitric oxide. Transport of ARG across the cell membrane determines intracellular substrate availability.
S. Zink, Malte Kelm, P. Rosen, H. Preiksteinhoff   +3 more
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The lung in the balance: arginine, methylated arginines, and nitric oxide

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2007
the lung is a major source of nitric oxide (NO), be it from nitric oxide synthase (NOS) III in the endothelium of the vast pulmonary circulation, NOS II in the epithelium of the large surface area of the airways, or NOS I in the nonadrenergic noncholinergic nerves ([6][1]).
openaire   +3 more sources

Vascular endothelial cells synthesize nitric oxide from L-arginine

Nature, 1988
R. Palmer, D. Ashton, S. Moncada
semanticscholar   +1 more source

Measurement of Arginine Vasopressin

2013
Arginine vasopressin (AVP) is a peptide hormone synthesised in the hypothalamus and secreted from nerve terminals within the posterior pituitary gland. Secretion is primarily under osmoregulatory control and levels rise in plasma in response to a body water deficit and are suppressed in response to water overload.
Nadia El-Farhan, M D Penney, David Hampton   +2 more
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The regulation, functions and clinical relevance of arginine methylation

Nature reviews. Molecular cell biology, 2019
E. Guccione, S. Richard
semanticscholar   +1 more source

Arginine and Disease States

The Journal of Nutrition, 1985
Studies of ammonia intoxication, orotic acid excretion and L-amino acid feeding regimens have provided new insights into the biological function of arginine. Recent data in near adults of carnivorous species raise doubts about the widely held view that arginine is needed in the diet only for optimum growth and that adults of mammalian species meet ...
openaire   +3 more sources