Results 101 to 110 of about 147,103 (258)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
COMUNICAREA, EMPATIA ŞI ASERTIVITATEA, DE LA ABILITATE LA COMPETENŢA PSIHOSOCIALĂ
Studia Universitatis Moldaviae: Stiinte ale Educatiei, 2011 The psychosocial skill signifies a person’s ability to control his emotions, to be able to argument his ideas, to be a good listener, to cooperate and creatively solve conflicts.
USM ADMIN
doaj
Arguments in Critical Thinking Ability [PDF]
Proceedings of the 1st Annual International Conference on Mathematics, Science, and Education (ICoMSE 2017), 2018 openaire +1 more source
Masked Abilities and the Four-Case Manipulation Argument
Canadian Journal of PhilosophyAbstract I offer a novel dispositional reply to Derk Pereboom’s four-case manipulation argument. Drawing on recent work in the metaphysics of dispositions, I argue that manipulated agents’ rational abilities are masked—prevented from manifesting as they otherwise would—by neuroscientists’ manipulation.
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The term consciousness and impressive evidence for cephalopod awareness
Animal SentienceMather presents comprehensive evidence of cephalopod cognitive ability and of a high level of awareness. The importance of taking account of the biological functioning and adaptations to the living environment is emphasised. An argument is presented that
Donald M Broom
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Profile of Learners Argumentation Ability on Socio-Scientific Issues
Jurnal Pijar MipaThis study aims to determine the profile of students' argumentation skills at MTs Idrisiyyah, Tasikmalaya Regency, in the context of Socio-Scientific Issues (SSI), which includes issues related to science and society based on the components of scientific argumentation from the Toulmin model.
Siva Fauziah +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source