Results 101 to 110 of about 145,010 (267)

Chromosome‐Level Genome Assemblies of Two Softshell Turtles with ZZ/ZW Provide Insights into TE‐Driven Recombination Suppression in Sex Chromosomes

Integrative Zoology, EarlyView.
This study presents the first genomic identification and characterization of ZW sex chromosomes in two soft‐shelled turtle species through genome assembly and resequencing. We reveal the structural organization of ZW chromosomes, identifying both pseudoautosomal regions (PARs) and differentiated regions.
Jianjun Liu, Zhiyuan Yang, Min Tang, Tingting Chen, Siqi Liu, Ziyao Meng, Xingjiang Bu, Xingquan Xia, Guang Yang, Liuwang Nie   +9 more
wiley   +1 more source

Exploring market dynamics of biological including biosimilar treatments for retinal diseases in Europe: An interrupted time‐series analysis

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the impact of biosimilar ranibizumab and on‐patent faricimab market entry on pricing and utilization trends and describe national variation in off‐label bevacizumab use in Europe. Methods Interrupted time series analysis of quarterly sales data (Q1 2018–Q2 2024) in 11 European countries evaluated ranibizumab utilization and ...
Elif Car, Isabelle Huys, Steven Simoens, Arnold G. Vulto   +3 more
wiley   +1 more source

Relationship Between PTBP1 and Pancreatic Cancer Based on microRNA and Behavior During TYMS‐Mediated Carcinogenesis

Cancer Science, EarlyView.
Corresponding Author and colleagues identify a pancreas‐enriched microRNA, miR‐216b‐5p, that suppresses PTBP1 and its downstream effector TYMS. Their findings reveal a novel miR‐216b‐5p/PTBP1/TYMS regulatory axis driving pancreatic cancer progression and establish PTBP1 as a central molecular regulator of tumor biology beyond its metabolic role ...
Shigenori Suzuki, Hiroaki Hase, Yosuke Inomata, Jun Arima, Kentaro Jingushi, Atsushi Tomioka, Nao Kawaguchi, Hiroki Hamamoto, Ryo Tanaka, Yoshiro Imai, Mitsuhiro Asakuma, Tomohito Tanaka, Kazutake Tsujikawa, Kohei Taniguchi, Sang‐Woong Lee   +14 more
wiley   +1 more source

Development of Chimeric Antigen Receptor‐Modified NK Cells for the Immunotherapy of Adult T‐Cell Leukemia/Lymphoma

European Journal of Haematology, EarlyView.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy with a poor prognosis and limited therapeutic options. ATL cells exhibit aberrant surface glycosylation patterns resulting from dysregulated glycosyltransferase expression, representing a potentially tumor‐specific therapeutic target.
Yuichiro Uchida, Seigo Tateo, Masahiro Wakao, Hiroyuki Shinchi, Hayate Sawayama, Akira Fukumoto, Makoto Yoshimitsu, Yasuo Suda   +7 more
wiley   +1 more source

The usage of the autoregressive integrated moving average (ARIMA) model for forecasting milk production in Egypt (2022-2025)

Open Veterinary Journal
Background: Milk considered one of the most important capital goods and essential source of animal protein in the diet of Egyptian family, as well as an effective mean to improve economic condition of farmers, considering this importance in view, the ...
Mohamed A. Omar, Fardos A.M. Hassan, Sara. E. Shahin, Marwa El-shahat   +3 more
doaj   +1 more source

Multivariate ARIMA and ARIMA-X Analysis:Package ‘marima’ [PDF]

, 2016
Multivariate arima and arima-x estimation using Spliid's algorithm.
openaire  

The relationship between ARIMA-GARCH and unobserved component models with GARCH disturbances [PDF]

The objective of this paper is to analyze the consequences of fitting ARIMA-GARCH models to series generated by conditionally heteroscedastic unobserved component models. Focusing on the local level model, we show that the heteroscedasticity is weaker in
Antoni Espasa, Esther Ruiz, Santiago Pellegrini   +2 more
core  

Causal Models as a Scientific Framework for Next‐Generation Ecosystem and Climate‐Linked Stock Assessments

Fish and Fisheries, EarlyView.
ABSTRACT Rapid changes in marine ecosystems highlight the need to account for time‐varying productivity in stock assessments used to support fisheries management. Common approaches incorporate annual variation or regressing processes such as recruitment, natural mortality, or growth on environmental variables.
J. Champagnat, C. C. Monnahan, J. Y. Sullivan, James T. Thorson, S. K. Shotwell, L. Rogers, A. E. Punt   +6 more
wiley   +1 more source

Temporal aggregaton of univariate linear time series models [PDF]

In this paper we feature state-of-the-art econometric methodology of temporal aggregation for univariate linear time series, namely ARIMA-GARCH models. We present a unified overview of temporal aggregation techniques for this broad class of processes and
Andrea, SILVESTRINI
core  

Removing observational noise from fisheries-independent time series data using ARIMA models [PDF]

, 2007
Abundance indices derived from fishery-independent surveys typically exhibit much higher interannual variability than is consistent with the within-survey variance or the life history of a species. This extra variability is essentially observation noise
Fogerty, Michael J., Stockhausen, William T.   +1 more
core