Results 11 to 20 of about 22,180 (202)

Adjunctive aripiprazole versus placebo for antipsychotic-induced hyperprolactinemia: meta-analysis of randomized controlled trials. [PDF]

open access: yesPLoS ONE, 2013
ObjectiveTo compare the safety and efficacy of adjunctive aripiprazole versus placebo for antipsychotic-induced hyperprolactinemia.MethodsPopulationadult patients presenting with antipsychotic-induced hyperprolactinemia diagnosed by prolactin level with ...
Xianbin Li, Yilang Tang, Chuanyue Wang
doaj   +1 more source

Aripiprazole salts. II. Aripiprazole perchlorate

open access: yesActa Crystallographica Section C Crystal Structure Communications, 2012
The molecular structure of aripiprazole perchlorate (systematic name: 4-(2,3-dichlorophenyl)-1-{4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl}piperazin-1-ium perchlorate), C23H28Cl2N3O2+·ClO4−, does not differ substantially from the recently published structure of aripiprazole nitrate [Freire, Polla & Baggio (2012).Acta Cryst.C68, o170–o173].
Freire Espeleta, Eleonora   +2 more
openaire   +3 more sources

Deep Brain Stimulation Reduces Conflict‐Related Theta and Error‐Related Negativity in Patients With Obsessive–Compulsive Disorder

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Obsessive–compulsive disorder (OCD) is a psychiatric disorder with alterations of cortico‐striato‐thalamo‐cortical loops and impaired performance monitoring. Electrophysiological markers such as conflict‐related medial frontal theta (MFT) and error‐related negativity (ERN) may be altered by clinically effective deep brain ...
Elena Sildatke   +9 more
wiley   +1 more source

Dose-response analysis of aripiprazole in patients with schizophrenia in Taiwan

open access: yesTherapeutic Advances in Psychopharmacology, 2022
Background: Aripiprazole is a third-generation antipsychotic agent with acceptable efficacy and a good safety profile. Previous studies have indicated the therapeutic serum concentration of aripiprazole to be 100 to 350 ng/ml; however, most of these ...
Yun Tien   +3 more
doaj   +1 more source

Aripiprazole salts. I. Aripiprazole nitrate

open access: yesActa Crystallographica Section C Crystal Structure Communications, 2012
The crystal structure of aripiprazole nitrate (systematic name: 4-(2,3-dichlorophenyl)-1-{4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl}piperazin-1-ium nitrate), C23H28Cl2N3O2+·NO3−or AripH+·NO3−, is presented and the molecule compared with the aripiprazole molecules reported so far in the literature. Bond distances and angles appear very similar,
Freire Espeleta, Eleonora   +2 more
openaire   +3 more sources

Aripiprazole sensitizes head and neck cancer cells to ionizing radiation by enhancing the production of reactive oxygen species

open access: yesPharmacology Research & Perspectives, 2022
Drug repositioning is an alternative process for drug development in cancer. Specifically, it is a strategy for the discovery of new antitumor drugs by screening previously approved clinical drugs.
Hyeon‐Jeong Jeong   +6 more
doaj   +1 more source

Dopamine receptor D2 activation suppresses the radiosensitizing effect of aripiprazole via activation of AMPK

open access: yesFEBS Open Bio, 2019
Drug repositioning has garnered attention as an alternative strategy to the discovery and development of novel anticancer drug candidates. In this study, we screened 321 FDA‐approved drugs against nonirradiated and irradiated MCF‐7 cells, revealing that ...
Hyounji Lee   +3 more
doaj   +1 more source

Effect of Aripiprazole on 5-HT2Receptor–mediated Wet-Dog Shake Responses and Disruption of Prepulse Inhibition in Rats

open access: yesJournal of Pharmacological Sciences, 2008
Aripiprazole, an atypical antipsychotic drug, is a D2dopamine–receptor partial agonist, but also has affinity to several serotonin receptors (5-HT1A,2A,2C,7).
Shuntaro Kohnomi   +3 more
doaj   +1 more source

Unique Effects of Acute Aripiprazole Treatment on the Dopamine D2 Receptor Downstream cAMP-PKA and Akt-GSK3β Signalling Pathways in Rats. [PDF]

open access: yesPLoS ONE, 2015
Aripiprazole is a wide-used antipsychotic drug with therapeutic effects on both positive and negative symptoms of schizophrenia, and reduced side-effects.
Bo Pan   +4 more
doaj   +1 more source

Pretreatment or Posttreatment with Aripiprazole Attenuates Methamphetamine-induced Stereotyped Behavior in Mice

open access: yesJournal of Experimental Neuroscience, 2015
Aripiprazole is a third-generation atypical antipsychotic and a dopamine D 2 receptor partial agonist. In the present study, we investigated whether a single administration of aripiprazole to mice, either as a pretreatment or as a posttreatment, would ...
Nobue Kitanaka   +6 more
doaj   +1 more source

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