Results 71 to 80 of about 22,180 (202)
pharma-kritik, 2004 Aripiprazol wird wegen seines besonderen Wirkungsmechanismus als «Dopamin-Serotonin-Stabilisator» bezeichnet. Es ist bei Schizophrenie ähnlich wirksam wie andere Neuroleptika. Aripiprazol verursacht keine Hyperprolaktinämie. Seine Vor- und Nachteile sind jedoch gesamthaft noch ungenügend definiert.
openaire +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.ABSTRACT Drug repurposing presents a cost‐effective and time‐efficient strategy to identify new therapeutic applications for existing drugs. Recent advances in artificial intelligence, including machine learning, deep learning, knowledge graphs, and natural language processing, have revolutionized this field by enabling automated discovery of drug ...
Alaba Bukola Ogungbite, Malusi Sibiya
wiley +1 more source
Regulated versus unregulated competition: How drug shortages boost illegal pharmacy sales
Strategic Management Journal, Volume 47, Issue 7, Page 1811-1839, July 2026.Abstract Research Summary This study examines how product shortages among legal firms create competitive opportunities for illegal firms. We analyze 713 drug shortages in the United States between 2017 and 2023 and show that shortages substantially increase illicit pharmacies’ sales of affected drugs, which rise by 40.5% during shortages and remain 32 ...
Luis Diestre, Benjamin Barber IV
wiley +1 more source
Acta Psychiatrica Scandinavica, Volume 154, Issue 1, Page 74-88, July 2026.ABSTRACT Background Psychotropic medications are associated with serious metabolic adverse effects, which contribute to an increased risk of cardiometabolic comorbidities in patients with severe mental illness (SMI). Several intervention strategies are available to mitigate these metabolic adverse effects; however, data on their utility in real‐world ...
Nicolette Stogios +17 more
wiley +1 more source
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.ABSTRACT Dopaminergic medication used in disorders like Parkinson's disease (PD) and restless legs syndrome can cause impulsive‐compulsive behaviour (ICB), often with strong negative effects on patients' quality of life. This narrative review presents translational evidence on iatrogenic ICB, taking findings from epidemiological, clinical, neuroimaging
Mirjam Wolfschlag +7 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren +8 more
wiley +1 more source
Amenorrhea associated with olanzapine normalized after switching to aripiprazole: a case report
European Journal of Psychotraumatology, 2012 Background : Amenorrhea as one of frequent adverse effects associated with the use of atypical antipyschotics is often neglected but can interrupt the compliance of treatment.
Alpay Ates +5 more
doaj +1 more source
Effectiveness of Alcohol Use Disorder Pharmacotherapies by Sex: Systematic Review and Meta‐Analysis
Drug and Alcohol Review, Volume 45, Issue 5, July 2026.ABSTRACT Issues Alcohol use disorder (AUD) shows sex‐related differences in prevalence, harm and treatment response. Despite growing interest in sex differences, evidence synthesis evaluating pharmacotherapy effectiveness by sex remains limited. Approach Web of Science, PubMed, Scopus, PsycINFO and Cochrane were searched twice.
Juliette Allen +11 more
wiley +1 more source
Early Intervention in Psychiatry, Volume 20, Issue 7, July 2026.ABSTRACT Aims The staging model in psychiatry is heuristic and evolving, provoking debate and stimulating alternative views. This paper reviews major controversies in the field of staging and prevention of psychosis. Methods We review the literature on the classification model, the continuum model and the dynamic systems model applied to psychiatry ...
Mark van der Gaag +10 more
wiley +1 more source
Early Intervention in Psychiatry, Volume 20, Issue 7, July 2026.ABSTRACT Background Eating disorders (ED) and psychosis/psychotic‐spectrum disorders (PSD) have overlapping symptoms and may co‐occur in a variety of presentations. Due to its debilitating and life‐threatening risk, it is important for clinicians to be aware of how catatonia may present within these co‐occurrences.
Rosiel Elwyn
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