Results 281 to 290 of about 1,029,823 (374)

Assessment of Pharmacokinetic Drug Interaction of Asciminib with Atorvastatin in Healthy Participants

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Asciminib is the first BCR::ABL1 inhibitor that Specifically Targets the ABL Myristoyl Pocket (STAMP) in patients with chronic myeloid leukemia. This phase 1, two‐treatment‐period, drug‐drug interaction study evaluated the effect of steady‐state asciminib on the pharmacokinetics of atorvastatin.
Matthias Hoch, Wendy Weis, Felix Huth, Seshulatha Jamalapuram, Michelle Quinlan, Amarnath Bandaru, Suleyman Eralp Bellibas, Asmae Mirkou, Shruti Kapoor, Shefali Kakar   +9 more
wiley   +1 more source

Computational Homogenisation and Identification of Auxetic Structures with Interval Parameters. [PDF]

Materials (Basel)
Beluch W, Hatłas M, Ptaszny J, Kloc-Ptaszna A.   +3 more
europepmc   +1 more source

Overlap between reading and arithmetic skills from primary to lower secondary school and the underlying cognitive mechanisms

, 2020
Heidi Korpipää
openalex   +1 more source

A Phase 1 Open‐Label Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a Single Intranasal Dose of Zavegepant in Healthy Chinese Adults

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Zavegepant is the only calcitonin gene‐related peptide antagonist approved as a nasal spray in the United States for acute treatment of migraine in adults with or without aura. This Phase 1, open‐label study evaluated the pharmacokinetics, safety, and tolerability of a single intranasal dose of zavegepant 10 mg in 12 healthy Chinese adults ...
Qiong Wei, Jufang Wu, Yangyi Dai, Jiaye Lin, Beikang Ge, Yanhui Sun, Jing Zhang, Jing Wang, Chen Li, Ding Ding, Jing Liu, Mohamed H. Shahin   +11 more
wiley   +1 more source

The Neural Bases of Graphical Perception: A Novel Instance of Cultural Recycling? [PDF]

J Cogn Neurosci
Ciccione L, Dehaene S.
europepmc   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

A Novel Arithmetic Optimization PDR Algorithm for Smartphones. [PDF]

Sensors (Basel)
Zhang M, Xu A.
europepmc   +1 more source

ESG Performance Evolution in Retail: A Systematic Review and Meta‐Analysis

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Environmental, social, and governance (ESG) practices have transformed from peripheral corporate social responsibility initiatives into core strategic imperatives in retail. Despite growing interest, the literature remains fragmented across disciplines and geographic contexts, with no comprehensive sector‐specific analysis examining the ...
Jiyeon Kim, Wooyoung Yang
wiley   +1 more source

Beyond valgus stress radiography: arithmetic HKA angle (aHKA) as a superior predictor of limb alignment after UKA. [PDF]

Arthroplasty
Nakano N, Tsubosaka M, Kamenaga T, Kuroda Y, Ishida K, Hayashi S, Kuroda R, Matsumoto T.   +7 more
europepmc   +1 more source

Microscopic time‐dependent mechanical behavior of shale derived from nanoindentation

Deep Underground Science and Engineering, EarlyView.
This study conducted grid nanoindentation creep tests to systematically analyze the microscopic creep behaviors of shale. Based on the analysis of creep strain rate sensitivity, the primary mechanism of microscopic creep in shale was found to be the extension and closure of microcracks.
Cunbao Li, Shilei Zhong, Heping Xie, Changtai Zhou, Jianjun Hu   +4 more
wiley   +1 more source