Results 51 to 60 of about 1,020,090 (322)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Arithmetic, 2022 This article aims to describe students' critical thinking ability in the application material of one-order differential equations, especially decay problems.
Arfatin Nurrahmah +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
Arithmetic, 2022 This study aims to design, develop, and produce media products in the form of math mobile learning applications assisted by Adobe Animate software about lines and angles that meet the criteria of validity and media practicality so that the media can be ...
Mohammad Zulfa Ainun Niam +1 more
doaj +1 more source
International Journal of Adaptive Control and Signal Processing, EarlyView.This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley +1 more source
Arithmetic, 2022 The research was conducted during the covid-19 pandemic and learning was carried out from and there were many technical obstacles and students' thinking abilities which tended to be low because they were unable to understand the material by being given ...
T.S. Hadi +3 more
doaj +1 more source
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Arithmetic, 2020 The objectives of this study were to: (1) describe the perceptions of students in the Mathematics Study Program of the Faculty of Science and Technology, Purwokerto University of Nahdlatul Ulama (UNU) on learning interactions between students and ...
Nur'aini Muhassanah +2 more
doaj +1 more source
Arithmetic, 2022 This study aims to increase student activity and learning outcomes by using the Missouri Mathematics Project (MMP) learning model on trigonometry equations. This research is a Classroom Action Research conducted in 3 cycles at MAN 1 Jombang. The subjects
Erviningsih Setyorini +2 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.Hydrostatic bearings excel in high‐precision applications, but their performance hinges on a continuous external supply. This study evaluates various material combinations for sliding surfaces to mitigate damage during supply failures or misalignment and to discover the most effective materials identified for enhancing the reliability and efficiency of
Michal Michalec +6 more
wiley +1 more source