Results 121 to 130 of about 15,323 (252)

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

NowPrecip 2: Precipitation nowcasting in the complex terrain of Switzerland. Part I: Methods

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
In this work we present the methods of the areal precipitation nowcasting system NowPrecip version 2. In this version a new methodology is introduced, which, although it shares philosophy and techniques with the original methodology of NowPrecip version 1, can be considered as distinct from that.
I. V. Sideris   +7 more
wiley   +1 more source

Lagrangian analysis of two flavours of Central European heatwaves: Formation under omega blocking versus initiation by subtropical ridges

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
We investigate whether Central European heatwaves (HWs) forming under omega blocking differ from those enabled by subtropical ridges, in terms of both air‐mass origin and processes warming air parcels along their way. Using ERA5‐based backward trajectories and a Lagrangian temperature anomaly decomposition, we identify significant differences in the ...
Alexander Lemburg   +3 more
wiley   +1 more source

The role of identification in data‐driven policy iteration: A system theoretic study

open access: yesInternational Journal of Robust and Nonlinear Control, EarlyView.
Abstract The goal of this article is to study fundamental mechanisms behind so‐called indirect and direct data‐driven control for unknown systems. Specifically, we consider policy iteration applied to the linear quadratic regulator problem. Two iterative procedures, where data collected from the system are repeatedly used to compute new estimates of ...
Bowen Song, Andrea Iannelli
wiley   +1 more source

Segzoo: a turnkey system that summarizes genome annotations. [PDF]

open access: yesBioinformatics
Mendez M   +3 more
europepmc   +1 more source

Climate Crisis, Human Mobility and Security Challenges in the MENA Region: Implications for Sustainable Development and Regional Stability

open access: yesSustainable Development, EarlyView.
ABSTRACT This study examines the interplay between climate change, violent conflict and forced migration in the Middle East and North Africa (MENA), focusing on asylum flows to the European Union (EU). By integrating high‐resolution climate, conflict and socioeconomic data spanning 2000 to 2023, we develop a comprehensive empirical framework to ...
Shifa Mathbout   +4 more
wiley   +1 more source

scMetaTraj: A Metabolism‐Centered Framework for Trajectory Inference in Single‐Cell Data

open access: yes
Med Research, EarlyView.
Jinwei Dai   +5 more
wiley   +1 more source

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