Results 181 to 190 of about 745,204 (238)

Coverage‐based rarefaction fails to quantify relative species richness

open access: yesOikos, EarlyView.
Coverage‐based rarefaction (CBR) is a high‐profile tool for assessing biodiversity that provides relative species richness estimates by leveraging the Good‐Turing index u to interpolate. In contrast to alternatives such as the Shannon and Simpson indices, CBR's main appeal is providing values in units of species. CBR is tested against a series of other
John Alroy
wiley   +1 more source

CAFs‐mediated histone lactylation reprograms cholesterol metabolism in colorectal cancer to drive CD8+ T cell immunosuppression

open access: yesThe Journal of Pathology, EarlyView.
Abstract The progression of colorectal cancer (CRC) is critically regulated by cancer‐associated fibroblasts (CAFs) within the tumor microenvironment (TME), yet the specific molecular mechanisms by which CAFs influence CRC remain unclear. This study reveals the mechanism by which CAFs promote CRC malignant progression and immune suppression through ...
Huachi Li   +6 more
wiley   +1 more source

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

open access: yesJournal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá   +4 more
wiley   +1 more source

Revisiting bare‐ground evaporation in a high‐resolution numerical weather prediction system

open access: yesQuarterly Journal of the Royal Meteorological Society, EarlyView.
An improved method is proposed to parameterize evaporation in numerical weather prediction models. The figure shows dew‐point temperature forecast error (standard deviation of forecast error and bias) versus lead time over the North Plains region during spring 2022 for three parameterizations: CTL, the α$$ \alpha $$ method of Jacquemin and Noilhan; IFS:
Vincent Fortin   +4 more
wiley   +1 more source

Brown–Proschan Repair Policy for Repairable Systems Using the Discrete Weibull Failure Distribution and Markov Chains

open access: yesQuality and Reliability Engineering International, EarlyView.
ABSTRACT A repairable system operates under a maintenance strategy involving scheduled preventive maintenance (PM) and corrective repair actions following failures. This study develops an exact analytical methodology using Markov chains with discrete states and time to calculate the expected number of failures E[N(t)]$\mathop {\mathbb {E}}[N(t)]$ under
Danilo G. O. Valadares   +3 more
wiley   +1 more source

Mathematical skills in deaf and hard-of-hearing children: A systematic review. [PDF]

open access: yesPLoS One
Laria C   +9 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy