Results 151 to 160 of about 44,238 (260)

Computer-assisted construction of <i>SU</i>(2)-invariant negative Einstein metrics. [PDF]

Ann Glob Anal Geom (Dordr)
Wang QS.
europepmc   +1 more source

A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of PF‐07261271 in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aim There is an unmet need for more effective therapies in inflammatory bowel disease (IBD). A single drug that blocks multiple distinct pathogenic pathways may offer therapeutic benefit superior to current monotherapies. PF‐07261271, a bispecific antibody targeting both the p40 subunit of interleukin‐12/23 and tumour necrosis factor‐like cytokine 1A ...
Srividya Neelakantan, Christopher Banfield, Kenneth Hung, Anna Sapone, Vivek Pradhan, Yuxi Zhao, Dana Parsons‐Rich, Grace Lee, Bryce G. Johnson, Elena Peeva, Michael S. Vincent, Valerie M. Clerin   +11 more
wiley   +1 more source

An Algorithmic Treatment of Causal Unit Selection. [PDF]

Entropy (Basel)
Huang H, Darwiche A.
europepmc   +1 more source

Effect of esomeprazole on the pharmacokinetics of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader, in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims The aim of this study is to evaluate the effects of multiple doses of esomeprazole, a strong proton pump inhibitor and acid‐reducing agent, on the pharmacokinetics and safety of vepdegestrant, a PROteolysis TArgeting Chimera oestrogen receptor degrader.
Lana Tran, Naihan Chen, Jennifer A. Winton, Kyle T. Matschke, Smita P. Goodman, Kimberly C. Lee, Yuanyuan Zhang, Weiwei Tan   +7 more
wiley   +1 more source

24-hour movement behaviors in association with academic performance in children and adolescents: cross-sectional compositional data analysis. [PDF]

J Act Sedentary Sleep Behav
Syväoja HJ, Kukko T, Asunta P, Hakonen H, Kulmala J, Lerkkanen MK, Räsänen P, Tammelin TH.   +7 more
europepmc   +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin, Marie A. Onyamboko, Caterina Fanello, Nicholas J. White, Nicholas P. J. Day, Richard M. Hoglund, Joel Tarning   +6 more
wiley   +1 more source

Non-Invasive Measurement of Cortical Plasticity in Brain Tumour Surgery: A Monocentric Experience of nTMS Mapping and Definition of Cognitive Reshaping Based on Tumour Histological Grade. [PDF]

Cancers (Basel)
Bonaudo C, Schapira ME, Pieropan E, Caredda C, Van Reeth E, Fedi F, Castaldi E, Baldanzi F, Troiano S, Maiorelli A, Pedone A, Visocchi E, Montcel B, Carrai R, Grippo A, Campagnaro L, Tola S, Della Puppa A.   +17 more
europepmc   +1 more source

Growth mindset is positively associated with mathematics attainment in Scotland—But socioeconomic status plays a greater role

British Educational Research Journal, EarlyView.
Abstract There is currently a gap in knowledge around pupils' growth mindset (GM) and attainment in Scotland, particularly in relation to Socioeconomic Status (SES). This study offers insights on the relevance of growth mindset in Scotland for attainment in mathematics by drawing on large‐scale data from the OECD's Programme for International Student ...
Catherine Reid, Ellen Boeren
wiley   +1 more source

Beyond language: A structured profile of number processing impairment in logopenic primary progressive aphasia. [PDF]

J Alzheimers Dis
Macoir J, Lavoie M, Laforce R.
europepmc   +1 more source

Single‐subject designs in character education: Methods for rigorous, contextual, and practitioner‐led research

British Educational Research Journal, EarlyView.
Abstract Character education research is often constrained by blunt methodological tools. Surveys capture breadth without depth; case studies offer richness but lack replicability; and randomised controlled trials (RCTs), though indispensable at the policy level, are costly, disruptive and ill‐suited to everyday practice with individual pupils.
Shane McLoughlin
wiley   +1 more source