Results 131 to 140 of about 12,228,153 (333)

Hypergeometric functions in arithmetic geometry

open access: yes, 2009
textHypergeometric functions seem to be ubiquitous in mathematics. In this document, we present a couple of ways in which hypergeometric functions appear in arithmetic geometry.
Salerno, Adriana Julia, 1979-
core  

Arithmetic subderivatives and Leibniz-additive functions [PDF]

open access: yes, 2019
We introduce the arithmetic subderivative of a positive integer with respect to a non-empty set of primes. This notion generalizes the concepts of the arithmetic derivative and arithmetic partial derivative.
Tossavainen, Timo   +5 more
core   +1 more source

Protein Structuromics Reveals a Loop‐Controlled Half‐Open Active Pocket Conformation Throughout Fe(II)/α‐ketoglutarate‐Dependent Dioxygenase Catalytic Cycle

open access: yesAdvanced Science, EarlyView.
This study reveals a conserved half‐open active pocket in Fe(II)/α‐ketoglutarate‐dependent dioxygenases through protein structuromics, distinguished by structural features comprising highly flexible loop elements. Enhanced sampling simulations‐guided mutagenesis experiments elucidated how this flexible loop regulates pocket open/closed conformations ...
Lunjie Wu   +10 more
wiley   +1 more source

Automated Extraction of Multicomponent Alloy Data Using Large Language Models for Sustainable Design

open access: yesAdvanced Science, EarlyView.
A large language model (LLM) based pipeline is developed to automatically extract a comprehensive and accurate multicomponent alloy database from literature corpus. The extracted dataset is integrated with sustainability indicators to identify potential alloys that outperform existing industrial benchmark materials in terms of both performance and ...
Aravindan Kamatchi Sundaram   +4 more
wiley   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

open access: yesAdvanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg   +18 more
wiley   +1 more source

DIFFERENCES IN THE DEVELOPMENT OF TACTILE FUNCTIONS IN PARTIALLY SIGHTED CHILDREN IN RELATION TO CATEGORY AND TYPE OF VISUAL IMPAIRMENT

open access: yesHuman Research in Rehabilitation, 2019
The aim of this study was to examine the differences in the development of tactile functions in visually impaired (amblyopic) children in relation to the category and type of visual impairment. In the study, 30 respondents with visual impairment, aged 7-
Dženana Radžo Alibegović   +2 more
doaj   +1 more source

Accurately Deciphering Tissue Heterogeneity From Spatial Multi‐Modal and Multi‐Omics With STransformer

open access: yesAdvanced Science, EarlyView.
STransformer is a unified deep learning framework designed to seamlessly accommodate a comprehensive landscape of spatial data. By simultaneously capturing short‐range cellular interactions and tissue‐wide semantic patterns, it extracts robust representations to accurately dissect complex tissue heterogeneity.
Xingyi Li   +9 more
wiley   +1 more source

Monotonicity Results for Arithmetic Means of Concave and Convex Functions

open access: yes, 2006
By majorization approaches, some known results on monotonicity of the arithmetic means of convex and concave functions are proved and generalized once ...
Xu, Tie-Quan, Qi, Feng, Shi, Huan-Nan
core  

Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis

open access: yesAdvanced Science, EarlyView.
Blood‐based amino acid patterns measured by 19F NMR reveal hidden metabolic changes in colorectal cancer. By analyzing how these amino acids interact as a network, machine learning models identify patients at higher risk of recurrence and metastasis.
Ji‐Yeon Lee   +9 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

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