Results 111 to 120 of about 3,476,772 (364)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Remarks Around Lorentz Transformation
, 2013 After diagonalizing the Lorentz Matrix, we nd the frame where the Dirac equation is one derivation and we calculate the 'speed' of the Schwarschild ...
Arm, Boris
core +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
The arm of a large-scale bronze statue from Aigion, Achaea, Greece
Dissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös NominataeThe arm of the large-scale bronze statue presented in the current research was handed over in 1951 to the Ephorate of Antiquities in Aigio of Achaia and constitutes a typical yet exquisite example of Peloponnesian oversized statuary in bronze.
Andreas G. Vordos
doaj +1 more source
TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
Journal of Minimally Invasive SurgeryPurpose: The aim of the study was to investigate whether wearing a forearm compression sleeve during robotic surgery (RS) reduces muscle fatigue. Methods : A randomized controlled study of consecutive RS cases was performed with three right-handed ...
Shing Wai Wong +5 more
doaj +1 more source
Electrical servo actuator bracket [PDF]
, 1981 An electrical servo actuator is mounted on a support arm which is allowed to pivot on a bolt through a fixed mounting bracket. The actuator is pivotally connected to the end of the support arm by a bolt which has an extension allowed to pass through a ...
Sawyer, R. V.
core +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Novel computation of pulse transit time from multi-channel PPG signals by wavelet transform
Current Directions in Biomedical Engineering, 2016 Being able to accurately monitor blood pressure in a reliable, truly non-invasive manner is a highly sought after goal within the biomedical community.
Pielmuş Alexandru-Gabriel +6 more
doaj +1 more source