Results 91 to 100 of about 2,018,863 (346)

Chairman's report / East Arm Hospital Management Board.

open access: yes, 1982
Aided by the experiences of the 1980-1981 period, the East Arm Hospital Management Board looked forward to its role for the next period. Between July 1981 to 31 March 1982 the Board made a significant contribution for the overall good of the hospital and

core  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Team Teaching Models in Primary Physical Education: Effects on Basic Motor Competencies and Self-Reported Physical Literacy

open access: yesChildren
Background/Objectives: To address the inconsistent provision of specialist physical education (PE) in primary schools, this study investigated the comparative efficacy of distinct team teaching configurations.
Gabriela Luptáková   +6 more
doaj   +1 more source

Determination of Hexabromocyclododecanes in Fish Using Modified QuEChERS Method with Efficient Extract Clean-Up Prior to Liquid Chromatography–Tandem Mass Spectrometry

open access: yesSeparations, 2020
A modified QuEChERS (quick, easy, cheap, effective, rugged, and safe) sample preparation method coupled with liquid chromatography–tandem mass spectrometry (LC–MS/MS) was proposed for the determination of α-, β-, and γ-hexabromocyclododecane (HBCD ...
Linda Okšová, Peter Tölgyessy
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Soong Classification Using X-Rays Only Moderately Correlates with Distal Radius Plate Position on Computed Tomography

open access: yesPlastic and Reconstructive Surgery, Global Open, 2022
Rachel Cross   +5 more
doaj   +1 more source

Failed Latarjet surgery: why, how, and what next?

open access: yesJSES International, 2020
Background: The Latarjet procedure is an established and popular procedure for recurrent anterior shoulder instability; however, to our knowledge, few studies have reported on the outcomes of revision for failed Latarjet surgery.
Umair Khan, MBChB, MRes(Dist)   +3 more
doaj   +1 more source

Salmon Arm Farmers' Exchange

open access: yes, 1912
See Centennial History of Salmon Arm, page 131 and Salmon Arm Scrapbook, page ...

core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

The arm of a large-scale bronze statue from Aigion, Achaea, Greece

open access: yesDissertationes Archaeologicae: Ex Instituto Archaeologico Universitatis de Rolando Eötvös Nominatae
The arm of the large-scale bronze statue presented in the current research was handed over in 1951 to the Ephorate of Antiquities in Aigio of Achaia and constitutes a typical yet exquisite example of Peloponnesian oversized statuary in bronze.
Andreas G. Vordos
doaj   +1 more source

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