Results 71 to 80 of about 2,792,974 (291)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

تأثیر حذف نوسان اندام فوقانی بر جابه‌جایی سه بعدی مرکز جرم بدن در حین راه رفتن

مجله دانشکده پزشکی اصفهان, 2019
Background: Since the effect of immobilization of the upper limb, despite its importance, is usually neglected in the analysis of gait, the purpose of the present study was to assess the effect of removal upper limb arm swing on 3-dimentional (3D) body ...
Razieh Yousefian-Molla, Heydar Sadeghi, Farzam Farahmand, Mohammad Ali Azarbayjani   +3 more
doaj   +1 more source

Distance to G14.33-0.64 in the Sagittarius Spiral Arm: H2O Maser Trigonometric Parallax with VERA

, 2010
We report on trigonometric parallax measurements for the Galactic star forming region G14.33-0.64 toward the Sagittarius spiral arm. We conducted multi-epoch phase-referencing observations of an H2O maser source in G14.33-0.64 with the Japanese VLBI ...
Hirota, Tomoya, Honma, Mareki, Iwadate, Kenzaburo, Kobayashi, Hideyuki, Miyaji, Takeshi, Reid, Mark J., Sato, Mayumi, Shibata, Katsunori M.   +7 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

ARM’s Perspective on the First Joint Clinical Assessments for ATMPs: Challenges and Opportunities on the Path Ahead

Journal of Market Access & Health Policy
Advanced Therapy Medicinal Products (ATMPs) are revolutionising modern medicine. By addressing the root cause rather than the symptoms of disease, ATMPs hold the promise of long-lasting benefits or even cures for severe, genetic, and rare diseases ...
Paolo Morgese, Stephen Majors, Dilip Patel   +2 more
doaj   +1 more source

The Arm Theory

, 2013
Did you ever wondered what is the Taylor formula for an arbitrary chosen basis ?
Arm, Boris
core   +1 more source

A multicountry randomized controlled trial of comprehensive maternal nutrition supplementation initiated before conception: the Women First trial. [PDF]

, 2019
Background: Reported benefits of maternal nutrition supplements commenced during pregnancy in low-resource populations have typically been quite limited.
Ali, Sumera A., Bauserman, Melissa, Bose, Carl L., Das, Abhik, Derman, Richard J., Dhaded, Sangappa M., Figueroa, Lester, Garcés, Ana, Goldenberg, Robert L., Goudar, Shivaprasad S., Hambidge, K. Michael, Koso-Thomas, Marion, Krebs, Nancy F., Lokangaka, Adrien, McClure, Elizabeth M., Pasha, Omrana, Sridhar, Amaanti, Stolka, Kristen, Thorsten, Vanessa R., Tshefu, Antoinette, Westcott, Jamie E.   +20 more
core   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Team Teaching Models in Primary Physical Education: Effects on Basic Motor Competencies and Self-Reported Physical Literacy

Children
Background/Objectives: To address the inconsistent provision of specialist physical education (PE) in primary schools, this study investigated the comparative efficacy of distinct team teaching configurations.
Gabriela Luptáková, Jaroslava Argajová, Tibor Balga, Dušana Augustovičová, Pavlína Sobotová, Gheorghe Balint, Branislav Antala   +6 more
doaj   +1 more source

The Arm Prime Factors Decomposition

, 2013
We introduce the Arm prime factors decomposition which is the equivalent of the Taylor formula for decomposition of integers on the basis of prime numbers. We make the link between this decomposition and the p-adic norm known in the p-adic numbers theory.
Arm, Boris
core   +1 more source