Results 51 to 60 of about 2,792,974 (291)

Parallaxes for W49N and G048.60+0.02: Distant Star Forming Regions in the Perseus Spiral Arm

open access: yes, 2013
We report trigonometric parallax measurements of 22 GHz H$_2$O masers in two massive star-forming regions from VLBA observations as part of the BeSSeL Survey. The distances of $11.11^{+0.79}_{-0.69}$ kpc to W49N (G043.16+0.01) and $10.75^{+0.61}_{-0.55}$
Brunthaler, A.   +6 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Estimating stiffness and damping of a novel variable impedance actuator based on adjusting viscoelastic properties of thermoresponsive polycaprolactone in harmonic motions

open access: yesScientific Reports
This paper presents a methodology to estimate the stiffness and damping of a novel variable impedance actuator designed to adjust its effective impedance by regulating the temperature of a thermoresponsive polymer, Polycaprolactone (PCL).
Trevor Exley   +2 more
doaj   +1 more source

Partnership at play: empowering Student Partners to navigate third space

open access: yesJournal of Learning Development in Higher Education
Solent Student Partner Programme is a cross-institutional, third-space project led by the central Education Office at Southampton Solent University in the UK.
Karen Arm
doaj   +1 more source

On the Spiral Structure of the Milky Way Galaxy

open access: yes, 2010
We consider the possible pattern of the overall spiral structure of the Galaxy, using data on the distribution of neutral (atomic), molecular, and ionized hydrogen, on the base of the hypothesis of the spiral structure being symmetric, i.e.
A. Cabrera-Lavers   +48 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Methodological and anatomical modifiers of Achilles tendon moment arm estimates implications for biomechanical modelling: Implications for biomechanical modelling [PDF]

open access: yes, 2012
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.Moment arms are important in many contexts. Various methods have been used to estimate moment arms.
Fath, Florian
core  

Unilateral versus bilateral upper limb training after stroke: The upper limb training after stroke clinical trial [PDF]

open access: yes, 2013
This article is available open access through the publisher’s website at the link below. Copyright © 2013 American Heart Association, Inc.Background and Purpose — Unilateral and bilateral training protocols for upper limb rehabilitation after stroke ...
Beek, PJ   +5 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Consumer Perception Towards Eco-friendly FMCGs in Coimbatore City

open access: yesInternational Journal of Bio-Resource and Stress Management, 2018
The environmental issues such as global warming, ozone depletion, water and air pollution, loss of species, and farmland erosion have led to the current alarming environmental crisis that threaten the environment as well as human life.
T. Samsai, S. Praveena, T. Nivetha
doaj  

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