Results 51 to 60 of about 2,868,786 (323)
Inflammation in benign prostate tissue and prostate cancer in the finasteride arm of the Prostate Cancer Prevention Trial [PDF]
, 2016 BACKGROUND: A previous analysis of the placebo arm of the Prostate Cancer Prevention Trial (PCPT) reported 82% overall prevalence of intraprostatic inflammation and identified a link between inflammation and higher-grade prostate cancer and serum PSA ...
Barber, John R +15 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Scientific ReportsThis paper presents a methodology to estimate the stiffness and damping of a novel variable impedance actuator designed to adjust its effective impedance by regulating the temperature of a thermoresponsive polymer, Polycaprolactone (PCL).
Trevor Exley +2 more
doaj +1 more source
Modeling of Motorized Orthosis Control
Applied Sciences, 2019 Orthotic devices are defined as externally applied devices that are used to modify the structural and functional characteristics of the neuro-muscular and skeletal systems.
Iñigo Aramendia +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
, 2014 We introduce the functional bandit problem, where the objective is to find an arm that optimises a known functional of the unknown arm-reward distributions.
Tran-Thanh, Long, Yu, Jia Yuan
core
A Molecular Spiral Arm in the Far Outer Galaxy
, 2011 We have identified a spiral arm lying beyond the Outer Arm in the first Galactic quadrant ~15 kpc from the Galactic center. After tracing the arm in existing 21 cm surveys, we searched for molecular gas using the CfA 1.2 meter telescope and detected CO ...
Abdo +12 more
core +1 more source
First steps towards the certification of an ARM simulator using Compcert [PDF]
, 2011 The simulation of Systems-on-Chip (SoC) is nowadays a hot topic because, beyond providing many debugging facilities, it allows the development of dedicated software before the hardware is available. Low-consumption CPUs such as ARM play a central role in
D. August +4 more
core +4 more sources
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source