Results 61 to 70 of about 11,731 (241)

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu   +4 more
wiley   +1 more source

A bundling problem revisited [PDF]

open access: yes, 2016
It was conjectured by M. Glasser and S. Davison and later proved by A. Eremenko that the certain animals should gather close to each other in order to decrease the total heat loss.
Ivanisvili, Paata
core   +1 more source

Phylogenetic multi-locus codon models and molecular clocks reveal the monophyly of haematophagous reduviid bugs and their evolution at the formation of South America.

open access: yes, 2010
We previously constructed a single molecular clock to date insect evolution that remains a cornerstone within entomological dating. The insect clock predicts that triatomine bugs, the vectors of South American trypanosomiasis, originated with the ...
Gaunt, Michael W, Patterson, James S
core   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano   +4 more
wiley   +1 more source

Especies locales, mercado y transporte en las investigaciones embriológicas: el estudio de la poliembrionía en armadillos a principios del siglo XX Local species, the market, and transportation in embryological research: the study of polyembryony in armadillos in the early twentieth century

open access: yesHistória, Ciências, Saúde: Manguinhos, 2008
Se examina en un caso concreto la afirmación general de la importancia de las redes de comunicación y la movilidad de las cosas para la ciencia. De qué forma esto jugó un papel relevante en las investigaciones sobre la embriología de ciertas especies de ...
Susana V. García
doaj   +1 more source

Linking regional and global functional trait data: insights from mammal communities in a fragmented Atlantic Forest landscape

open access: yesOikos, EarlyView.
Accurate functional trait data are essential for understanding ecosystem services and processes in fragmented landscapes. We evaluated whether the global EltonTraits 1.0 database adequately represents the functional structure of mammal communities in forest fragments and restoration sites in a highly fragmented Atlantic Forest landscape.
Maria F. R. Godoi   +5 more
wiley   +1 more source

The intervals method : a new approach to analyse finite element outputs using multivariate statistics [PDF]

open access: yes, 2017
Background. In this paper, we propose a new method, named the intervals' method, to analyse data from finite element models in a comparative multivariate framework.
De Esteban-Trivigno, Soledad   +3 more
core   +3 more sources

Differences in mammal community response to highway construction across different levels of human land use

open access: yesWildlife Biology, EarlyView.
Worldwide, transportation agencies have been involved in road mitigation efforts to reduce road mortality and promote connectivity of endangered species. Baseline data on how mammals respond to highway construction, however, are rarely collected in road mitigation and monitoring studies, including in the USA.
Thomas J. Yamashita   +4 more
wiley   +1 more source

Exotic origins: the emblematic biogeographies of early modern scaly mammals [PDF]

open access: yes, 2015
This is the accepted manuscript. It is currently embargoed pending publication.Exotic natural objects brought to Europe in the sixteenth and seventeenth centuries were mutable and malleable things.
Lawrence, Natalie
core   +2 more sources

Wildlife temporal behaviors in response to human activity changes during and following COVID‐19 park closures

open access: yesWildlife Biology, EarlyView.
With urbanization reducing the amount of available wildlife habitat, and outdoor recreation increasing the human activity within wildlife habitats, it is important to understand the effects of human activity on animal behavior. This study examined how the reduction in human presence in urban parks in Gainesville, Florida, affected the temporal ...
Maya Fives, Matthew Hallett
wiley   +1 more source

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