Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Sixty years of the Military Technical Courier: Origins of the military technical thinking in the military printing of the Kingdom of Serbia [PDF]
The article sheds light on the origins of the military technical thinking in the military publishing of the Kingdom of Serbia with a view to marking a jubilee - the sixtieth anniversary of the Military Technical Courier.
Ivan B. Mijatović
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Warrior Cops: The Ominous Growth of Paramilitarism in American Police Departments [PDF]
Over the past 20 years Congress has encouraged the U.S. military to supply intelligence, equipment, and training to civilian police. That encouragement has spawned a culture of paramilitarism in American law enforcement.
Diane Cecilia Weber
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Metalware and Pottery from the Khmelevka I Settlement
The paper deals with the objects of armament, horse equipment and daily life from the Hmelevka I settlement of the second half of 13th – 14th cc. The settlement is located in the Saratov Volga region and was studied by expedition of Kazan University ...
Leonard F. Nedashkovsky +1 more
doaj +1 more source
The Success of the Light Armoured Vehicle [PDF]
In order to understand the purchase of military vehicles, one must understand the vehicle and where it falls in the evolution of vehicle procurement. This article, written in response to an earlier article in response to an earlier article in Canadian ...
Storey, Ed
core +1 more source
Teaching new media composition studies in a lifelong learning context [PDF]
Governmental proposals for lifelong learning, and the role of Information and Learning Technologies/Information Communication Technologies (ILT/ICT) in this, idealistically proclaim that ILT/ICT empowers learners.
Jameson, Jill, Squires, David
core +2 more sources

