Results 101 to 110 of about 1,846,966 (339)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Redai diliWith the advancement of the "Belt and Road" initiative, China's investment in Africa has increased steadily in recent years, and trade volume has expanded continuously. However, due to the frequent occurrence of armed conflicts in Africa, the security of
Pi Shuaishuai, Ba Rui, Yang Xuan
doaj +1 more source
From 'Mercenaries' to 'private security contractors': The (re)construction of armed security providers in international legal discourses [PDF]
, 2011 The proliferation of armed security contractors in Iraq and Afghanistan has led to widespread criticism of their insufficient control through international laws and conventions.
Krahmann, E
core +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
War Crimes Committed in Non-International Armed Conflicts
ACROSSThe international society of the 21st century has made it imperative to eliminate impunity for international crimes. To this end, a number of mechanisms have been created to repress and punish crimes against peace, humanity, and war crimes.
Olga DORUL, Andrei NASTAS
doaj +1 more source
High-technologies, armed conflicts and human security [PDF]
, 2016 El examen de las amenazas para la seguridad y el bienestar de las personas inherentes al concepto de seguridad humana exige ocuparse también de las consecuencias que la utilización de las altas tecnologías puedan ocasionar en relación con los conflictos ...
Mar García Rico, Elena del
core
World Development, 2020 This article studies the impact of COVID-19 on armed conflict. The pandemic has significant health, economic and political effects. These can change the grievances and opportunity structures relevant for armed conflicts to either increase or decrease conflict risks.
openaire +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source