Results 71 to 80 of about 612,946 (306)
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Collaboration with criminal organisations in Colombia: an obstacle to economic recovery
Those seeking to support economic development for internally displaced people in Colombia need to understand how and why many IDPs collaborate with armed groups and criminal organisations.
Christopher M Hays
doaj
DDR and the Internal Organization of Non-State Armed Groups
This paper argues that demobilization, disarmament and reintegration (DDR) trajectories of non-state armed groups are shaped by a group’s internal organization.
Brian McQuinn
doaj +1 more source
This article presents a personal experience from the collaboration with the organization SER PAZ (Being Peace). The NGO works in Guayaquil, Ecuador, with armed juvenile groups.
Seisdedos, Beatriz
core
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
This paper deals with using word embedding models to trace the temporal dynamics of semantic relations between pairs of words. The set-up is similar to the well-known analogies task, but expanded with a time dimension.
Kutuzov, Andrey +2 more
core +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Unmasking Militants: Organizational Trends in Armed Groups, 1970-2012: RESEARCH NOTE. [PDF]
Malone I.
europepmc +1 more source

