Results 191 to 200 of about 28,205 (301)

Second‐generation prokineticin PKR1 receptor agonists: Advancing cardioprotection against chemotherapy‐induced toxicity

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 12, Page 3377-3394, June 2026.
IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand   +8 more
wiley   +1 more source

Association of Inflammasome Gene Expression Levels with Pathogenesis of Familial Mediterranean Fever in Armenians. [PDF]

open access: yesInt J Mol Sci
Hayrapetyan V   +8 more
europepmc   +1 more source

Structure and sequence evolution in the pennycress (Thlaspi arvense) pangenome

open access: yesNew Phytologist, Volume 250, Issue 5, Page 2723-2741, June 2026.
Summary Eukaryotic genomes harbor many forms of variation, including nucleotide diversity and structural polymorphisms, which experience natural selection and contribute to genome evolution and biodiversity. Harnessing this variation for agriculture hinges on our ability to detect, quantify, catalog, and deploy genetic diversity. Here, we explore seven
Kevin A. Bird   +25 more
wiley   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

open access: yesAdvanced Science, Volume 13, Issue 26, 8 May 2026.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin   +17 more
wiley   +1 more source

Cassava production systems optimized for double output: Seed‐cuttings and root yields

open access: yesAgronomy Journal, Volume 118, Issue 3, May/June 2026.
Abstract Cassava (Manihot esculenta Crantz) is a strategic crop for food security but continues to face major challenges related to low root yields and the lack of optimized systems for producing high‐quality seed‐cuttings. This study evaluated the effects of different planting densities, varieties, and agrochemical‐based seed‐cutting treatments ...
Marcos de Souza Campos   +4 more
wiley   +1 more source

“The Future Is Ancestral”: The Environmental Cuir Utopias of Gabriela Cabezón Cámara

open access: yesFuture Humanities, Volume 4, Issue 1, May 2026.
ABSTRACT Argentinian author Gabriela Cabezón Cámara identifies as a “socio‐environmentalist and writer” and has been actively involved in the feminist movement #NiUnaMenos since 2015, alongside her growing engagement with environmental activism. She advocates for Indigenous land rights, water accessibility, and challenges offshore petroleum extraction ...
Victoria Jara
wiley   +1 more source

Home - About - Disclaimer - Privacy