Results 91 to 100 of about 984,623 (303)

Bottom‐Up Engineering of a Human Neuromuscular System for Modeling Activity‐Induced Remodeling, Metabolic Stress, and Endothelial‐Modulated Excitability

open access: yesAdvanced Materials, EarlyView.
Using a bottom‐up approach, we engineered a human neuromuscular microchip to investigate distinct adaptive responses to neural stimulation and metabolic stress. Further integration of endothelial cells revealed their critical role in modulating neuromuscular excitability, establishing a comprehensive neurovascular‐muscular model.
Jinchul Ahn   +17 more
wiley   +1 more source

Italy and Arms Control: Identity Dilemmas [PDF]

open access: yesСовременная Европа
The article analyses the evolution of Italy's foreign policy on the most important multilateral treaties in the field of arms control, their proliferation and disarmament.
Nadezhda Arbatova
doaj   +1 more source

Toward Perception‐Native Electronic Skin: Bio‐Inspired In‐/Near‐Sensor and Neuromorphic Computing for Humanoid Robots

open access: yesAdvanced Materials Technologies, EarlyView.
Dense tactile streams from across the humanoid body converge on collide in a central wiring and data bottleneck. By relocating computation closer to and then into the skin itself, near‐ and in‐sensor architectures, together with neuromorphic computing, chart a path toward perception‐native electronic skin, in which the conversion of stimulus into ...
Mijin Kim   +6 more
wiley   +1 more source

miRNA expression changes during the course of neoadjuvant bevacizumab and chemotherapy treatment in breast cancer

open access: yesMolecular Oncology, 2019
One of the hallmarks of cancer is sustained angiogenesis. Favorable results have been reported in some breast cancer (BC) patients receiving antiangiogenic therapy with bevacizumab (Bev) in combination with chemotherapy, and further knowledge on how Bev ...
Evita Maria Lindholm   +8 more
doaj   +1 more source

AI‐Powered Framework for Evaluating Drug Efficacy for Three‐Dimensional In Vitro Cancer Models in Robot‐Assisted Production

open access: yesAdvanced Robotics Research, EarlyView.
An AI‐powered, robot‐assisted framework automatically produces, images, and analyzes 3D tumor spheroids to evaluate drug efficacy. Integrated modules handle spheroid formation, live/dead staining, brightfield imaging, and automated image analysis, including spheroid segmentation, viability and metrics to assess the drug treatment efficacy. The workflow
Dalia Mahdy   +13 more
wiley   +1 more source

A Superlubricated Magnetically Steerable Microcatheter with Integrated Optical and Fluidic Channels

open access: yesAdvanced Robotics Research, EarlyView.
A magnetically steerable microcatheter with integrated optical and fluidic channels is developed for multifunctional navigation in tortuous anatomical environments. A surface‐grafted hydrogel coating enables low‐friction actuation. The device demonstrates stable light and fluid delivery during magnetic manipulation, offering a compact platform for ...
Yuntian Du   +5 more
wiley   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

open access: yesAdvanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu   +8 more
wiley   +1 more source

Clyde Street 2-16, 1972

open access: yes, 1972
View of 2-16 Clyde Street, the buildings on the right have already been demolished, the "Bakers Arms" can be clearly seen in this ...
Calow, Dennis;
core  

The Consequences of a Lab Escape of a Potential Pandemic Pathogen

open access: yesFrontiers in Public Health, 2014
Lynn Charles Klotz   +2 more
doaj   +1 more source

From the International Nuclear Non-Proliferation Regime to the Global Zero Regime: An Introduction

open access: yesJournal for Peace and Nuclear Disarmament
This supplementary issue of the Journal for Peace and Nuclear Disarmament reassesses the international nuclear disarmament and non-proliferation regime at a time of profound geopolitical transformation.
Mitsuru Kurosawa, Fumihiko Yoshida
doaj   +1 more source

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