Results 71 to 80 of about 224,122 (264)
The Armed Forces of the Ottoman Empire in the Crimean War: Evaluating in the Past and in the Present
Military actions of allies in the Crimean War of 1853-1856 had the coalition character, and therefore it is quite problematic to evaluate the contribution of individual troops objectively.
Semen N. Osipovskiy
doaj +1 more source
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
Designer Dynamic DNA Nanoaggregate in Living Cell for Mitochondrial Energy Restriction
This study presents the Tech‐tetrahedron, a designer dynamic DNA nanoaggregate engineered for precise mitochondrial energy restriction. Its trinity‐functionalized design integrates navigable unit, telomerase‐activated latch, and self‐assembly module.
Ruijia Deng +12 more
wiley +1 more source
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang +8 more
wiley +1 more source
For over four years, soldiers have been sent to the Polish-Belarusian border to support the border guards in counteracting illegal migration. Participation in these activities affects their relationships with their families and their opinions about ...
Dariusz CZEKAJ
doaj +1 more source
Safe and precise bioorthogonal therapy of tumors was achieved by an ultrasound‐responsive heterostructured nanoreactor with on‐demand catalytic activity. Under piezoelectric catalysis, the system undergoes reversible Pd2+/Pd0 redox cycling, concurrently enabling spatiotemporally controlled prodrug activation and self‐terminating catalytic dose ...
Daqing Xia +9 more
wiley +1 more source
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao +11 more
wiley +1 more source
This work aims to carry out an analysis of the process of militarization suffered Colombia in the decades of the 60' and 70', after the introduction into the country of the doctrine of national security, a move of American foreign ...
Mauricio Puentes Cala
doaj

