Results 81 to 90 of about 224,122 (264)

Grand Tour Correspondence in the Time of War: The Early Stages of the War of the Spanish Succession in the Letters of Henry Bentinck, Viscount Woodstock and His Tutor Paul Rapin-Thoyras (1701–1702)

open access: yesFaces of War
Letters sent during a Grand Tour, an early modern educational journey, are often considered important sources for the history of tourism and travel, history of diplomacy or family relations.
Michaël Green
doaj   +1 more source

The Invisible Army [PDF]

open access: yesJournal of Clinical Microbiology, 2017
ABSTRACT The “invisible army” of clinical microbiologists is facing major changes and challenges. The rate of change in both the science and technology is accelerating with no end in sight, putting pressure on our army to learn and adapt as never before. Health care funding in the United States is undergoing dramatic change which will require
openaire   +2 more sources

HMGCR‐Driven Cholesterol Metabolism Promotes Osteoarthritis Progression by Accelerating Synovial Fibroblast Senescence

open access: yesAdvanced Science, EarlyView.
In the pathological context of osteoarthritis (OA), the phosphorylation of AKT1 at Ser473 enhances its binding to Lys140 of Insig1, which facilitates the formation of AKT1–Insig1 complex. Subsequently, the activation of AKT1 promotes the phosphorylation of Insig1 at Ser189, potentially enhancing the dissociation of Insig1 from sterol regulatory element‑
Xiaoqi Zhang   +19 more
wiley   +1 more source

Generation and Enhancement of Persistent Nanoscale Magnetization in All‐Dielectric Metasurfaces by Optically Injected and Localized Free Carriers

open access: yesAdvanced Science, EarlyView.
Infrared metasurface‐guided waves (IR‐MGW) scattered by a time interface (TI) induced by rapid, localized free‐carrier generation can be efficiently rectified to generate strong, persistent magnetic fields. We develop a rigorous, theoretical model to study a time‐varying, dispersive medium and uncover the redistribution of the initial energy of the IR ...
Shivaksh Rawat   +2 more
wiley   +1 more source

HISTORY OF SAVATE (FRENCH BOXING) IN SERBIA FROM XIX CENTURY TILL THE END OF THE FIRST WORLD WAR [PDF]

open access: yesSport Mont, 2010
The second half of XIX century in Serbian national history is the period of constant struggle for independance initiated by Serbian Revolution in 1804. As a result of both, the historical events and the wakening of national consciousness, awareness for ...
Dejan Gavrilović   +2 more
doaj  

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao   +6 more
wiley   +1 more source

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

open access: yesAdvanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang   +5 more
wiley   +1 more source

Resilience and Emotional Intelligence in Spanish Army Personnel: The Impact of Marital Status

open access: yesPsychology International
Background: The relationship between resilience and emotional intelligence and its influence on military personnel has become the object of research in recent years, since today’s combatant faces significant physical and psychological challenges ...
José Gabriel Soriano-Sánchez
doaj   +1 more source

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