Therapeutic Fasting as a Novel Approach to Mitigate Musculoskeletal Symptoms in Breast Cancer Patients undergoing Aromatase Inhibitor Therapy: A Feasibility Study Protocol. [PDF]
Meyer H +10 more
europepmc +1 more source
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping +7 more
wiley +1 more source
CDK4/6 inhibitor in combination with aromatase inhibitor effective in metastatic hidradenocarcinoma. [PDF]
Glatzel V +6 more
europepmc +1 more source
Sex Differences in Cancer Immunotherapy—Clinical Evidence and Mechanisms With a Focus on NSCLC
ABSTRACT Accumulating evidence suggests that the immune system shows subtle but relevant differences between men and women. These differences may have an impact on cancer development and TME composition as well as responses to and adverse events elicited by immunotherapies.
Eva Krieghoff‐Henning +4 more
wiley +1 more source
Abstract Testosterone and oestrogens play significant roles in female physiology, extending beyond reproductive functions to influence brain health, mood regulation, and behaviour. Testosterone low‐dose therapy is increasingly considered for alleviating sexual dysfunction symptoms in postmenopausal women, and has been recently investigated as therapy ...
Manon Dubol +9 more
wiley +1 more source
Real-world effectiveness of palbociclib plus an aromatase inhibitor in HR+/HER2- MBC patients living in disadvantaged neighborhoods. [PDF]
Lynce F +6 more
europepmc +1 more source
Adaptive Changes Result in Activation of Alternate Signaling Pathways and Acquisition of Resistance to Aromatase Inhibitors [PDF]
Angela Brodie, Gauri Sabnis
openalex +1 more source
Abstract More women than men are diagnosed with Alzheimer's disease (AD). Sex hormones have been ascribed neuroprotective properties, and their decline, particularly the reduction of estrogen during menopause, has been implicated in AD risk. In this study, we examined how loss of circulating sex hormones affects cognitive performance and amyloid ...
Patricia Muñoz +10 more
wiley +1 more source
Determination and Disposition of the Aromatase Inhibitor Exemestane in CYP3A-Deficient Mice. [PDF]
Taheri H +4 more
europepmc +1 more source
Survival benefit of tamoxifen and aromatase inhibitor in male and female breast cancer
Holm Eggemann +3 more
openalex +2 more sources

