Results 171 to 180 of about 57,705 (278)

Aromatase Inhibitors: Are There Differences Between Steroidal and Nonsteroidal Aromatase Inhibitors and Do They Matter? [PDF]

, 2008
William R. Miller, John M.S. Bartlett, Angela Brodie, Robert W. Brueggemeier, E. Di Salle, Per Eystein Lønning, Antonio Llombart‐Cussac, Nicolaì Maass, Thierry Maudelondé, Hironobu Sasano, Paul E. Goss   +10 more
openalex   +1 more source

Protective Effects of Hesperidin on Letrozole‐Induced Neurotoxicity: Involvement of Oxidative Stress, Apoptotic Signaling, and Inflammation

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 3, March 2026.
Letrozole induces neurotoxicity by promoting oxidative stress, inflammation, and apoptotic signaling in the brain. Hesperidin co‐treatment mitigates these effects by restoring redox balance, suppressing pro‐inflammatory cytokines, and normalizing Bax/Bcl‐2–mediated apoptotic pathways, thereby exerting neuroprotective effects.
İdris Ayhan, Munevver Nazlican Kaplan, Demet Dondu Kasim, Ozlem Ozmen, Osman Ciftci   +4 more
wiley   +1 more source

Sex Hormones Attenuate Pro‐Inflammatory Gene Expression in Nucleus Pulposus and Annulus Fibrosus Cells in a Cell‐Type Specific Manner

JOR SPINE, Volume 9, Issue 1, March 2026.
Methodological overview of primary bovine NP and AF cell culture. Pro‐ and anti‐inflammatory gene and protein expression analyses were performed after 24 h of pro‐inflammatory stimulus, followed by 3 days of cotreating cells with sex hormones in addition to pro‐inflammatory cytokines.
Jeffrey L. Hutchinson, Andrew E. Leung, Cheryle A. Séguin   +2 more
wiley   +1 more source

Nutritional Impact on Breast Cancer in Menopausal and Post-Menopausal Patients Treated with Aromatase Inhibitors. [PDF]

Cancers (Basel)
Popescu R, Flangea C, Vlad DC, Cobec IM, Seropian P, Marina CD, Vlad T, Dumitrascu AL, Puscasiu D.   +8 more
europepmc   +1 more source

Comparison of docking procedures and its efficiency for Betasecretase, Aromatase and Pyruvate dehydrogenase kinase inhibitors

, 2017
Zahra Rezaei, Masood Fereidoonnezhad, Zeinab Faghih, Hossein Sadeghpur, Ayyub Mojaddami, Amirhossein Sakhteman   +5 more
openalex   +2 more sources

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Pharmacophoric Investigation of a Natural Product-like Class of Aromatase Inhibitors Using Molecular Modeling. [PDF]

ACS Omega
Held A, Esselman A, Huebner M, Frietas G, Boyson B, Walker M, Miller B.   +6 more
europepmc   +1 more source

Aromatase inhibitors of the third generation in endocrine therapy of breast cancer and endometrial cancer: the successes and failures of the combination therapy

, 2016
Ekaterina P Fadeeva, Alla Lisyanskaya, G. Manikhas, Ruslan I. Glushakov, Natalia I Tapilskaya   +4 more
openalex   +2 more sources

Ribociclib with an Aromatase Inhibitor for Previously Untreated, HR-Positive, HER2-Negative, Locally Advanced or Metastatic Breast Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal [PDF]

, 2018
Nasuh Büyükkaramikli, Saskia de Groot, Rob Riemsma, Debra Fayter, Nigel Armstrong, Piet J. M. Portegijs, Steven Duffy, Jos Kleijnen, Maiwenn Al   +8 more
openalex   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source