Results 191 to 200 of about 57,705 (278)

Aromatase overexpression and breast hyperplasia, an in vivo model--continued overexpression of aromatase is sufficient to maintain hyperplasia without circulating estrogens, and aromatase inhibitors abrogate these preneoplastic changes in mammary glands. [PDF]

, 1999
Rajeshwar R. Tekmal, Nameer B. Kirma, Kiran Gill, Keith A Fowler   +3 more
openalex   +1 more source

Non-Steroidal Aromatase Inhibitor [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

INSL3 Expression in Leydig Cells is a Biomarker for Immunocastration in Boars: Transcriptional Evidence

Andrology, Volume 14, Issue 3, Page 782-795, March 2026.
ABSTRACT Background Study aimed to obtain insights into physiological responses to immunocastration in pubertal boars by evaluating effects of alternative vaccination protocols and identifying a reliable immunocastration biomarker. Objectives It was hypothesized that the timing of gonadotropin‐releasing hormone (GnRH) suppression by immunocastration ...
Nina Batorek Lukač, Martin Škrlep, Klavdija Poklukar, Petra Ferjan, Volker Stefanski, Gregor Fazarinc, Milka Vrecl   +6 more
wiley   +1 more source

Response to "Aromatase Inhibitors and Dementia Risk: Putting Safety Into Perspective". [PDF]

Pharmacol Res Perspect
Yuste MT, Sainz-Gil M, Escudero E, Marín P.   +3 more
europepmc   +1 more source

A Transcriptomic Analysis of Cancer‐Stromal Interactome in Lung Cancer Xenograft Models

Cancer Science, Volume 117, Issue 3, Page 841-851, March 2026.
We conducted a comprehensive analysis of the lung cancer interactome to identify key ligand–receptor pairs involved in the aggressiveness of lung adenocarcinoma. Tumor necrosis factor superfamily member 12 and its receptor tumor necrosis factor receptor superfamily member 12A signaling axis may be potential candidates for therapeutic intervention for ...
Yuriko Takayama‐Isagawa, Daisuke Komura, Takayuki Isagawa, Yusuke Amano, Atsushi Kihara, Tamaki Miura, Taichiro Yoshimoto, Hiroyoshi Tsubochi, Kazutaka Fujita, Koichi Hagiwara, Makoto Maemondo, Tetsuo Ushiku, Shumpei Ishikawa, Noriyoshi Fukushima, Kentaro Inamura, Daisuke Matsubara, Toshiro Niki   +16 more
wiley   +1 more source

An integrated computational, in vitro and metabolomics approach to the discovery of novel aromatase inhibitors with anti-breast cancer activities. [PDF]

Sci Rep
Maiuthed A, Chatwichien J, Sandech N, Yang MC, Krobthong S, Rukthong P, Svasti J, Ruchirawat S, Eurtivong C.   +8 more
europepmc   +1 more source

P050 Contribution of estrone sulfate to cell proliferation in aromatase-inhibitor resistant breast cancer

, 2015
Takako Higuchi, Mikiko Endo, Toru Hanamura, Tatsuyuki Gohno, Toshimitsu Niwa, Y Yamaguchi, Jun Horiguchi, Izumi Takeyoshi, Seitaku Hayashi   +8 more
openalex   +1 more source

Endocrine Resistance Score Based on Three Key Genes Predicts Prognosis and Reveals Potential Therapeutic Targets for ER+HER2− Breast Cancer

Cell Proliferation, Volume 59, Issue 3, March 2026.
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping, Lewei Zhu, Nian Chen, Xikun Liu, Jirui Zhong, Xiaoqing Sun, Hailin Tang, Kaiming Zhang   +7 more
wiley   +1 more source

Sex Differences in Cancer Immunotherapy—Clinical Evidence and Mechanisms With a Focus on NSCLC

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Accumulating evidence suggests that the immune system shows subtle but relevant differences between men and women. These differences may have an impact on cancer development and TME composition as well as responses to and adverse events elicited by immunotherapies.
Eva Krieghoff‐Henning, Balagopal Pai, Maike Collienne, Isabel Ben‐Batalla, Sonja Loges   +4 more
wiley   +1 more source

Aromatase Inhibitors and Dementia Risk: Putting Safety Into Perspective. [PDF]

Pharmacol Res Perspect
Rizk M, Mokbel K.
europepmc   +1 more source