Results 141 to 150 of about 17,390 (287)

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

Catalytic acceptorless complete dehydrogenation of cycloalkanes

Nature Communications
The advancement of an effective hydrogen liberation technology from liquid organic hydrogen carriers, particularly cycloalkanes such as cyclohexane and methylcyclohexane, holds significance in realizing a hydrogen-centric society. However, the attainment
Rahul A. Jagtap, Yuki Nishioka, Stephen M. Geddis, Yu Irie, Tsukasa Takanashi, Rintaro Adachi, Akira Yamakata, Masaaki Fuki, Yasuhiro Kobori, Harunobu Mitsunuma, Motomu Kanai   +10 more
doaj   +1 more source

Aerobic Palladium(II)-Catalyzed Dehydrogenation of Cyclohexene-1-carbonyl Indole Amides: An Indole-Directed Aromatization

, 2016
A palladium­(II)-catalyzed oxidative dehydrogenation of cyclohexene-1-carbonyl indole amides yielding the corresponding benzoylindoles is reported. The new aromatization is also applied to functionalized indoles such as tryptamine and tryptophan.
Sandeep R. Kandukuri (2037451), Martin Oestreich (1353330)   +1 more
core   +1 more source

Perinatal women dominantly protect—rather than submissively cede—resources when interacting with threatening‐looking others

British Journal of Psychology, EarlyView.
Abstract When competing for resources, people appear particularly sensitive to social cues of threat, tending to submissively cede resources to more (vs. less) threatening‐looking others. This tendency appears especially pronounced among those that are physically weaker and thus more vulnerable to harm.
Valentina Proietti, Ilenia Mastroianni, Valentina Silvestri, Martina Arioli, Viola Macchi Cassia, Shawn N. Geniole   +5 more
wiley   +1 more source

Simultaneous aromatization of propane and higher alkanes or alkenes over H-GaAlMFI zeolite

, 1996
Conversion of propane in its aromatization over H-GaAlMFI zeolite can be enhanced by a factor of about two by carrying out the aromatization simultaneously with that of higher alkanes or alkenes; this is mostly due to hydrogen-transfer reactions between ...
Choudhary, V. R., Choudhary, T. V., Kinage, A. K.   +2 more
core   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Halogencarbene-free Ciamician-Dennstedt single-atom skeletal editing

Nature Communications
Single-atom skeletal editing is an increasingly powerful tool for scaffold hopping-based drug discovery. However, the insertion of a functionalized carbon atom into heteroarenes remains rare, especially when performed in complex chemical settings ...
Shaopeng Liu, Yong Yang, Qingmin Song, Zhaohong Liu, Paramasivam Sivaguru, Yifan Zhang, Graham de Ruiter, Edward A. Anderson, Xihe Bi   +8 more
doaj   +1 more source

Life Course Trajectories of Body Mass Index and Risk of Cancer in Adulthood: Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to identify common life‐course body mass index (BMI) trajectories (childhood/adulthood to adulthood) and their impact on risk of cancer overall and cancer at different sites in adulthood. Methods Observational studies were identified that assessed the association of BMI trajectories with
Samira Behboudi‐Gandevani, Tommy Haugan, Nayla Cristina Do Vale Moreira, Ellen Christin Arntzen, Moira Strand Hutchinson, Melanie Nichols, Razieh Bidhendi‐Yarandi   +6 more
wiley   +1 more source

Deoxytrifluoromethylation/aromatization of cyclohexan(en)ones to access highly substituted trifluoromethyl arenes

Nature Communications
Trifluoromethyl arenes (Ar–CF3) are amongst the commonly encountered fluorinated substructures in pharmaceutical, agrochemical, and material sciences. However, predominant methods to access Ar–CF3 possess several limitations, including harsh conditions ...
Pankaj Bhattarai, Mohammed K. Abd El-Gaber, Suvajit Koley, Ryan A. Altman   +3 more
doaj   +1 more source

Development of a Novel Solid State Organic Fluorophore: Excited-State Aromatization-Induced Structural Planarization

Solid-state emission is pivotal for the functionality of organic compounds in opto-electronic applications. Yet, tailoring the emission characteristics of existing solid-state emissive organic frameworks is a challenging task, primarily due to their ...
Timothy, Schmidt, Binh, Khanh Mai, William, Kendrick, Domenic, Pace, Thanh Vinh, Nguyen, Reece, Crocker, Wallace, Wong, Bolong, Zhang   +7 more
core   +1 more source