Results 41 to 50 of about 664,460 (300)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

A Topology-Based Array Compensation Empowered by Equivalent Current Modeling of TM₁₀ Patch Antennas for Cross-Polarization Reduction

IEEE Open Journal of Antennas and Propagation
This paper introduces a comprehensive analysis of cross-polarization effects originating from current imbalances in patch antennas and array configurations.
Taeyeong Yoon, Uichan Park, Minje Kim, Sanghun Lee, Young-Seok Lee, Sangwook Nam, Jungsuek Oh   +6 more
doaj   +1 more source

Simulation of the influence of hydrophones used for the characterization of pressure field distribution in low frequency, high power ultrasonic reactor vessels [PDF]

, 2007
This paper describes the use of a finite element (FE) modeling approach to investigate the influence of different hydrophone designs in laboratory scale reactor vessels.
Gachagan, A., Harvey, G., O'Leary, R.L.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Performance Evaluation of Partial Shading Detection for Photovoltaic Generation Systems: A Comparative Study of Array Configurations

IEEE Access
Partial Shading Detection (PSD) can determine whether PS occurs and assist in selecting the appropriate Maximum Power Point Tracking (MPPT) algorithm, thereby improving the performance of Photovoltaic Generation Systems (PVGS).
Jen-Hao Teng, Han-Cheng Wu, Chun-Wei Cheng   +2 more
doaj   +1 more source

Element Configuration Optimization of Hybrid Distributed PA-MIMO Radar System Based on Target Detection

Leida xuebao, 2023
This paper establishes a hybrid distributed Phased-Array Multiple-Input Multiple-Output (PA-MIMO) radar system model, which combines coherent processing gain and spatial diversity gain to synergistically improve the target detection performance.
Cheng QI, Junwei XIE, Haowei ZHANG, Zihang DING, Xiao YANG   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A framework for determining improved placement of current energy converters subject to environmental constraints

International Journal of Sustainable Energy, 2018
A modelling framework identifies deployment locations for current-energy-capture devices that maximise power output while minimising potential environmental impacts.
Kurt Nelson, Scott C. James, Jesse D. Roberts, Craig Jones   +3 more
doaj   +1 more source