Results 51 to 60 of about 134,685 (302)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Element Configuration Optimization of Hybrid Distributed PA-MIMO Radar System Based on Target Detection

Leida xuebao, 2023
This paper establishes a hybrid distributed Phased-Array Multiple-Input Multiple-Output (PA-MIMO) radar system model, which combines coherent processing gain and spatial diversity gain to synergistically improve the target detection performance.
Cheng QI, Junwei XIE, Haowei ZHANG, Zihang DING, Xiao YANG   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

A framework for determining improved placement of current energy converters subject to environmental constraints

International Journal of Sustainable Energy, 2018
A modelling framework identifies deployment locations for current-energy-capture devices that maximise power output while minimising potential environmental impacts.
Kurt Nelson, Scott C. James, Jesse D. Roberts, Craig Jones   +3 more
doaj   +1 more source

Influence of array configuration on MIMO channel capacity [PDF]

2008 IEEE Antennas and Propagation Society International Symposium, 2008
The use of multiple antennas at each side of the radio link has demonstrated an increase in terms of data bit rate and spectral efficiency [1]. Due to this, different techniques such as spatial multiplexing and space-frequency-time techniques are being applied to MIMO (Multiple-Input Multiple-Output) systems.
Gómez Calero, Carlos, Martínez Rodríguez-Osorio, Ramón   +1 more
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A Systematic Method of Interconnection Optimization for Dense-Array Concentrator Photovoltaic System

The Scientific World Journal, 2013
This paper presents a new systematic approach to analyze all possible array configurations in order to determine the most optimal dense-array configuration for concentrator photovoltaic (CPV) systems.
Fei-Lu Siaw, Kok-Keong Chong
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Testing for the programming circuit of LUT-based FPGAs

, 1997
The programming circuit of look-up table based FPGAs consists of two shift registers, a control circuit and a configuration memory (SRAM) cell array. Because the configuration memory cell array can be easily tested by conventional test methods for RAMs ...
T. Inoue, Okamoto, Takuji, H. Michinishi, Yokohira, Tokumi, Inoue, Tomoo, T. Yokohira, T. Okamoto, Michinishi, Hiroyuki, Fujiwara, Hideo, H. Fujiwara   +9 more
core   +1 more source

ELECTROMAGNETIC LAUNCH SYSTEM BASED ON A HALBACH ARRAY CONFIGURATION [PDF]

Scientific Journal of Silesian University of Technology. Series Transport, 2018
The paper analyses a new configuration of an electromagnetic launch system (EMLS) able to accelerate a 1-kg mass projectile at a muzzle velocity of 3,000 m/s with an acceleration length of 10 m.
Laurian GHERMAN, Constantin ROTARU, Marian PEARSICA   +2 more
doaj   +1 more source