Results 91 to 100 of about 778,732 (345)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

An Under-Sampled Line Array Element Signal Reconstruction Method Based on Compressed Sensing Theory

open access: yesArchives of Acoustics
The half-wavelength spacing arrangement of underwater uniform linear arrays has been widely used for better anti-interference performance and higher signal gain.
Tongjing SUN, Mengwei ZHOU, Lei CHEN
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Beamforming Techniques for Multichannel audio Signal Separation

open access: yes, 2012
Beamforming is a signal processing technique. It has been studied in many areas such as radar, sonar, seismology and wireless communications, to name but a few.
Adel, Hidri   +3 more
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Design of Spectrally Compatible Waveforms With Low Auto‐ and Cross‐Correlation‐Weighted Integrated Sidelobe Levels

open access: yesIET Radar, Sonar & Navigation
Low‐correlation sidelobes are critical for spectrally compatible waveforms in multiple‐input multiple‐output (MIMO) radar systems. This study presents a novel algorithm for designing spectrally compatible waveforms for MIMO radar with low auto‐ and cross‐
Zhaobo Jia, Lei Yu, Yinsheng Wei
doaj   +1 more source

A novel ML DOA estimation algorithm for array signal processing

open access: yesMATEC Web of Conferences, 2018
A novel algorithm for finding the optimal solution of nonlinear function in maximum likelihood DOA estimation is proposed to reduce the calculation in multi-dimensional nonlinear search of the estimation.
Shi Pengfei   +3 more
doaj   +1 more source

Wide-bandwidth high-resolution search for extraterrestrial intelligence [PDF]

open access: yes
This interim report summarizes the research accomplished during the initial 6-month period of the grant. Activities associated with antenna configurations, the channelizing downconverter, the fast Fourier transform array, the DSP (digital signal ...
Horowitz, Paul
core   +3 more sources

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